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Abstract  

Endohedral 133Xe-higher fullerenes (133Xe@C76 and 133Xe@C84) were produced by implantation of 133Xe ions using an isotope separator. A high performance liquid chromatography (HPLC) analysis showed that the peak of endohedral 133Xe-higher fullerenes shifted backward from that of empty fullerenes, suggesting a possibility of the separation of endohedral 133Xe-higher fullerenes from empty fullerenes. The yields of endohedral 133Xe-fullerenes were in the order of 133Xe@C76<133Xe@C84<133Xe@C60<133Xe@C70.

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Journal of Radioanalytical and Nuclear Chemistry
Authors: S. Watanabe, Y. Iida, N. Suzui, T. Katabuchi, S. Ishii, N. Kawachi, H. Hanaoka, S. Matsuhashi, K. Endo, and N. Ishioka

Abstract  

Copper-64 was produced by the 64Ni(p, n)64Cu reaction using enriched 64NiO target. We investigated and compared the production yield of 64Cu for proton beams of various energies by using a thick target. Enriched 64Ni was recovered with high yield by simple procedures. Imaging studies using positron emission tomography (PET) and positron emitting tracer imaging system (PETIS) were performed. We obtained clear images in PET and PETIS studies. The results of this study indicate that 64Cu can be utilized as a biomedical tracer for the molecular imaging both in animals and plants.

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Journal of Radioanalytical and Nuclear Chemistry
Authors: S. Watanabe, N. Ishioka, T. Sekine, A. Osa, M. Koizumi, H. Shimomura, K. Yoshikawa, and H. Muramatsu

Abstract  

Ion implantation was applied to the production of endohedral 133Xe-fullerene. Using an isotope separator, 133Xe ions were implanted into a fullerene target of C60 and C70 produced by vacuum evaporation on a Ni backing. An HPLC analysis following dissolution of the fullerene targets in o-dichlorobenzene corroborated the formation of 133Xe@C60 and 133Xe@C70, showing a strong correlation between C60/C70 and 133Xe. The observed tailing following 133Xe peaks in the elution curves suggests a possibility of the isolation of endohedral 133Xe-fullerene from empty fullerene.

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Abstract  

The radionuclide 67Cu was produced via the 68Zn(p,2p)67Cu reaction by irradiating enriched 68Zn targets with 70 MeV proton beam. Copper-67 was chemically separated from the zinc target by ion-exchange chromatography using Chelex-100 chelating ion-exchange resin. Procedure for recovery of the enriched 68Zn was developed. The target recovery yield of this method was evaluated to be more than 97%.

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Summary  

Hydrophilic endohedral 133Xe-fullerenols, [133Xe@C60(OH)xand 133Xe@C70(OH)x], were synthesized from hydrophobic endohedral 133Xe-fullerenes. The yield of endohedral 133Xe-fullerenols extracted in water was about 40% and 23% for C60and C70, respectively. The products stored in 0.9% NaCl solution at 20 °C were stable enough to be used in nuclear medicine.

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Journal of Radioanalytical and Nuclear Chemistry
Authors: N. Ishioka, H. Matsuoka, S. Watanabe, A. Osa, M. Koizumi, T. Kume, S. Matsuhashi, T. Fujimura, A. Tsuji, H. Uchida, and T. Sekine

Abstract  

The positron emitters11C,13N and18F and their labeled compounds have been produced for studies on plants using a newly developed positron emitting tracer imaging system. Although this system covers, at present, a limited area in a plant, the distribution of the positron emitter fed into the plant can be visualized dynamically. Further development of positron-emitter-labeled compounds is expected to elucidate the physiological function of plants in vivo.

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