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  • Author or Editor: Rade Marković x
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Experimental R M values for a series of functionalized 2-alkylidene-4-oxothiazolidines and 1,2-dithioles have been determined by reversed-phase TLC on RP-18 silica plates. Binary mixtures of methanol and water, tetrahydrofuran and water, and acetone and water were used as mobile phases. R M 0 values were determined for these mobile phase mixtures by linear extrapolation to 0% ( v/v ) organic modifier. The lipophilicity, C 0 , was calculated as the ratio of the intercept and slope values. Chromatographically obtained lipophilicity data correlated well with calculated log P values.

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