Authors:T. Sykes, L. Stephens-Newsham, M. Apps, and A. Noujaim
Compounds of both gold and platinum are used in medicine, the former as salts to treat arthritides and the latter as the metal
complex cisplatin to treat cancer. We have investigated neutron activation analysis with the Slowpoke II reactor as an assay
method for both elements using human blood plasma as a matrix. Neutron activation of platinum gives rise to 3.15 day199Au while that of gold produces 2.7 day198Au. Activated samples are dissolved during heating in test tubes and the gold extracted by adding dibutyl sulphide to the
same tube. The latter is formed to able to quantitate Pt down to 60 ng and Au down to 60 pg. The dissolution technique and
possible interferences in the assay are discussed.