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  • Author or Editor: V. Mártha x
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Abstract  

The heat, equilibrium, and kinetics of adsorption of 1-ethoxy-2-propanol vapours on granulated activated carbon were determined simultaneously by a reaction calorimeter SETARAM C80 D at T=298.15 K at various relative vapour pressures (0.1< p/p s<0.8). The adsorption isotherm was correlated by the Freundlich equation. It was observed that the enthalpies of adsorption decrease slightly with increasing of the relative vapour pressure of the adsorptive. The rate of adsorption were calculated from analysis of the heat flux signals and it was found that the mass-transfer coefficient for 1-ethoxy-2-propanol vapours in granulated activated carbon increased with increasing relative vapour pressure of the adsorptive.

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Abstract

Despite the significant associations between the short (S) allele of the serotonin transporter-linked polymorphic region (5-HTTLPR) and various psychiatric disorders, the S allele has persisted at relatively high prevalence in the human population worldwide. Based on findings of greater amygdala activity among S allele carriers both at rest and in response to threat-relevant stimuli, the S allele appears to be associated with greater vigilance for danger; therefore we hypothesized that the S allele would be associated with lower scores on risk-related traits. In order to test this hypothesis we assessed the 5-HTTLPR genotype of 81 individuals of European ancestry and tested for an effect of genotype on two dimensions of risk-related behavior: venturesomeness and impulsivity. Results revealed significantly lower venturesomeness and a trend toward lower impulsivity associated with the S allele. We speculate that relatively greater vigilance for and avoidance of danger may counteract the disease risk associated with the 5-HTTLPR S allele and contribute to its persistence at high prevalence in the human population. Replication in a larger sample is necessary in order to confirm these associations.

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