Authors:T. Biczók, Sz. Kassai, and V. A. Gyarmathy
There has been a recent increase in interest in chia seeds as a growing number of people try to observe a healthy lifestyle, particularly healthy eating habits. Given the increasing popularity of chia seeds in Hungary as well, we performed a study to examine what information on chia seeds is available on Hungarian websites.
Materials and Methods
We conducted a systematic, qualitative content analysis to examine the first 200 Hungarian results of a Google search on “chia seeds”.
We identified five main topics: 1. general information, 2. effects/side-effects, 3. modes of preparation, 4. target audience, and 5. tone of the article. Sometimes information (especially on the effects) was presented in a sensationalist manner, and some claims were not scientifically well-founded, but rather based on subjective opinion.
In the online media, chia seed consumption was mainly recommended for those who are trying to lose weight and for diabetics, even though there is currently no proof that it can improve the condition of such people. Further studies are needed to demonstrate and confirm claims related to the beneficial effects of the chia seed. Until this has been done, readers of Google-search results – especially those who have a health condition – should be cautious about certain statements published on non-scientific websites.
Authors:G. Molnár, V. A. Gyarmathy, J. Takács, S. Sándor, B. Kiss, J. Fazakas, and P. L. Kanizsai
Conditions that have similar initial presentations as sepsis may make early recognition of sepsis in an emergency room (ER) difficult. We investigated whether selected physiologic and metabolic parameters can be reliably used in the emergency department to differentiate sepsis from other disease states that mimic it, such as dehydration and stroke.
Loess regression on retrospective follow-up chart data of patients with sepsis-like symptoms (N = 664) aged 18+ in a large ER in Hungary was used to visualize/identify cutoff points for sepsis risk. A multivariate logistic regression model based on standard triage data was constructed with its corresponding receiver operating characteristic (ROC) curve and compared with another model constructed based on current sepsis guidelines.
Age, bicarbonate, HR, lactate, pH, and body temperature had U, V, W, or reverse U-shaped associations with identifiable inflexion points, but the cutoff values we identified were slightly different from guideline cutoff values. In contrast to the guidelines, no inflexion points could be observed for the association of sepsis with SBP, DPB, MAP, and RR and therefore were treated as continuous variables. Compared to the guidelines-based model, the triage data-driven final model contained additional variables (age, pH, bicarbonate) and did not include lactate. The data-driven model identified about 85% of sepsis cases correctly, while the guidelines-based model identified only about 70% of sepsis cases correctly.
Our findings contribute to the growing body of evidence for the necessity of finding improved tools to identify sepsis at early time points, such as in the ER.
Authors:E. Kovács, D. Pilecky, Z. Szakál-Tóth, A. Fekete-Győr, V.A. Gyarmathy, L. Gellér, B. Hauser, J. Gál, B. Merkely, and E. Zima
We investigated the effect of age on post-cardiac arrest treatment outcomes in an elderly population, based on a local database and a systemic review of the literature.
Data were collected retrospectively from medical charts and reports. Sixty-one comatose patients, cooled to 32–34 °C for 24 h, were categorized into three groups: younger group (≤65 years), older group (66–75 years), and very old group (>75 years). Circumstances of cardiopulmonary resuscitation (CPR), patients' characteristics, post-resuscitation treatment, hemodynamic monitoring, neurologic outcome and survival were compared across age groups. Kruskal-Wallis test, Chi-square test and binary logistic regression (BLR) were applied. In addition, a literature search of PubMed/Medline database was performed to provide a background.
Age was significantly associated with having a cardiac arrest on a monitor and a history of hypertension. No association was found between age and survival or neurologic outcome. Age did not affect hemodynamic parameter changes during target temperature management (TTM), except mean arterial pressure (MAP). Need of catecholamine administration was the highest among very old patients. During the literature review, seven papers were identified. Most studies had a retrospective design and investigated interventions and outcome, but lacked unified age categorization. All studies reported worse survival in the elderly, although old survivors showed a favorable neurologic outcome in most of the cases.
There is no evidence to support the limitation of post-cardiac arrest therapy in the aging population. Furthermore, additional prospective studies are needed to investigate the characteristics and outcome of post-cardiac arrest therapy in this patient group.