Authors:R. Leite, W. Jacob-Filho, M. Saiki, L. Grinberg, and R. Ferretti
Neutron activation analysis was applied to assess trace element concentrations in brain tissues from normal (n = 21) and demented individuals (n = 21) of both genders aged more than 50 years. Concentrations of the elements Br, Fe, K, Na, Rb, Se and Zn were determined.
Comparisons were made between the results obtained for the hippocampus and frontal cortex tissues, as well as, those obtained
in brains of normal and demented individuals. Certified reference materials, NIST 1566b Oyster Tissue and NIST 1577b Bovine
Liver were analyzed for quality of the analytical results.
Authors:M. Saiki, N. Sumita, O. Jaluul, W. Jacob-Filho, and M. Vasconcellos
In this study, blood serum trace elements, biochemical and hematological parameters were obtained to assess the health status
of an elderly population residing in São Paulo city, SP, Brazil. Results obtained showed that more than 93% of the studied
individuals presented most of the serum trace element concentrations and of the hematological and biochemical data within
the reference values used in clinical laboratories. However, the percentage of elderly presenting recommended low density
lipoprotein (LDL) cholesterol concentrations was low (70%). The study indicated positive correlation between the concentrations
of Zn and LDL-cholesterol (p < 0.06).
Authors:M. Saiki, N. M. Sumita, O. Jaluul, I. F. Sobreiro, W. Jacob Filho, and M. B. A. Vasconcellos
In this study a protocol for blood serum analysis was defined and the concentrations for Br, Ca, Cl, Fe, Na, Rb, Se and Zn
were obtained by instrumental neutron activation analysis. Blood samples were collected from healthy elderly volunteers who
were selected based on the SENIEUR protocol. Contamination of blood by the collection procedure was also evaluated and found
negligible. The serum was separated by centrifugation, then freeze-dried and analyzed. Most of results obtained were within
the acceptable value ranges used by physicians for normal population. The certified reference material, NIST SRM 1566b Oyster
Tissue was analyzed for quality control.