Authors:Ekoko Gracien, Zhou Ruimin, Li Jian, Xin Hui, and Tondozi Keto
Gamma-irradiation has been applied to synthesize the nanocomposite semiconductor constituted of zinc and cadmium sulfide Cd1-xZnxS ultra fine particles at room temperature by utilizing homogeneous release of S2– ions from the decomposition of sodium thiosulfate. The structure, morphology, size and optical properties of that compound have been studied by X-ray powder diffraction (XRD), transmission electron microscopy (TEM) and ultraviolet-visible spectrometer (UV-visible). The product obtained from irradiated solutions containing zinc ions, cadmium ions and the sulfur source has been characterized as a composite of (CdxZn1-x)S, with spherical morphology and with a diameter of average size of about 5.3 nm. The possible mechanism of formation of the composite is proposed.
Authors:Ling Zhang, Huan Zhao, Qiushi Li, Juan Wang, and Xin Tan
An article assessment system based on both Tianjin University and nine key Chinese Universities’ academic disciplinary benchmarks
was established to evaluate researcher’s published papers. With this scientific benchmarking system, the quality of a researcher’s
papers could be easily located in a percentile scale in corresponding field within certain groups. Several factors, including
total number of papers, order of authors, impact of journals, citation count, h-index, e-index, a-index, m-quotient, etc.,
were also utilized for both quantity and quality analysis. Furthermore, the novel proposed weighted citation analysis was
introduced to judge a researcher’s contribution to his/her research outcomes. The convenient application and comprehensive
evaluation property of this assessment system was thoroughly discussed via a given example.
Authors:Jifen Wang, Huaqing Xie, Yang Li, and Zhong Xin
Phase change nanocomposites were prepared by dispersing γ-Al2O3 nanoparticles into melting paraffin wax (PW). Intensive sonication was used to make well dispersed and homogeneous composites.
Differential scanning calorimetric (DSC) and transient short-hot-wire (SHW) method were employed to measure the thermal properties
of the composites. The composites decreased the latent heat thermal energy storage capacity, Ls, and melting point, Tm, compared with those of the PW. Interestingly, the composites with low mass fraction of the nanoparticles, have higher latent
heat capacity than the calculated latent heat capacity value. The thermal conductivity of the nanocomposites was enhanced
and increased with the mass fraction of Al2O3 in both liquid state and solid state.
Authors:Li Yu-guo, Huang Xuan, Liu Riu-li, Li Qing-nuan, Zhang Xiao-dong, and Li Wen-xin
The water-soluble fullerene derivative C60(OH)x was radiolabeled with 67GaCl3. The labeling yields were determined by radio-PLC. The effects of pH, reaction time, temperature and the amount of C60(OH)x on the labeling yields were studied. The stability of 67Ga-C60(OH)x was also examined. The results showed that the labeling yields could reach 97% under the best labeling conditions and the radiochemical purity of 67Ga-C60(OH)x solution kept at 37 °C remained at 88% after 212 hours. The biodistribution studies of 67Ga-C60(OH)x in mice showed a high localization of 67Ga-C60(OH)x in the bone marrow, bone, liver and spleen with slow clearance and a negligible accumulation in the blood. These data suggest that the water-soluble C60(OH)x, having the same properties as microcolloids, may be used as a carrier of drug system for lymphatic targeting.
Authors:Ping Shi, Xiao-Xin Li, Wei Zhu, Hong Yang, Chi Dong, and Xiao-Ming Li
C-reactive protein (CRP) is an established marker of inflammation and has been proposed to play a proinflammatory role in pathologies of several diseases. CRP is primarily produced by the liver and released into circulation as a pentameric molecule composed of five identical subunits. It has been suggested that the activation of the proinflammatory actions of CRP requires sequential conformational changes triggered by local inflammatory conditions. These include the dissociation into the subunit form (monomeric CRP, mCRP) and further reduction of the intra-subunit disulfide bond of mCRP. This model predicts that mCRP is the primary isoform present in inflamed but not healthy tissues, however the supporting evidence is lacking. Herein, we stained tissue samples across multiple anatomical locations from several types of human diseases with highly selective monoclonal antibodies that can differentiate CRP and mCRP. The results indicated that mCRP is the predominant form existing in the lesions. Further immunoblotting of the patient tissue samples revealed the potential presence of reduced mCRP. Together, we conclude that mCRP but not CRP is the major isoform present in local inflammatory lesions, supporting the so-called cascading model of CRP function and regulation.