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Journal of Flow Chemistry
Authors: Xin Li, Anbang Chen, Yangzhi Zhou, Lingling Huang, Zheng Fang, Haifeng Gan, and Kai Guo

Continuous-flow synthesis of coumarin was realized in a tandem microflow system containing two microreactors in this study. Generally, better reaction yield (91%) and less side reaction were obtained in the flow system compared with conventional method. Interestingly, different reaction pathways were observed between continuous-flow system and batch methods.

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