Authors:Zs. Szántó, É. Svingor, M. Molnár, L. Palcsu, I. Futó, and Z. Szűcs
Understanding the characteristics of diffusion is essential in the assessment of radionuclide release through the backfill of waste repository. The diffusion behavior of 3H, 99Tc, 125I, 36Cl and 85Sr in granite, concrete and bentonite was studied in a specially designed diffusion cell. Diffusion coefficients (D, Da) and time-lag (ta) were measured, break-trough curves were plotted and experimental data were interpreted to predict diffusion rates. The results showed that tritium, iodine and chlorine could be considered as non-sorbing tracers, while technetium was weakly and strontium was strongly sorbed (no break-through was observed during the period of the experiments).
Authors:Z. Szántó, L. Benkő, B. Gasz, G. Jancsó, Ö. P. Horváth, and E. Rőth
Resection and subsequent end-to-end anastomosis of the windpipe is a tried-and-tested acceptable method for the surgical treatment
of segmental defects. There are a variety of different techniques for tracheal end-to-end anastomosis, but controversial reports
highlight the fact that the suturing technique of the anastomosis is still subject of debate. We aimed to show the postoperative
effects of the continuous and simple interrupted suturing technique respectively on the tracheal cartilage using differential
scanning calorimetry. Transsection and subsequent reanastomosis of the cervical trachea was performed in 14 adult beagle dogs.
The trachea was anastomized with continuous or simple interrupted sutures respectively depict no change in microcirculation
after the resection of the trachea, but significant decrease following the completion the anastomosis with continuous sutures.
Conventional histological analysis did not show any marked postoperative change in the tracheal cartilage but our DSC scans
clearly demonstrated the differences between the intact cartilages and the ones involved in the anastomosis.
Authors:L. Benkő, J. Danis, M. Czompo, R. Hubmann, A. Ferencz, G. Jancsó, Z. Szántó, A. Zólyomi, F. Könczöl, Á. Bellyei, E. Rőth, and D. Lőrinczy
Massive bleeding from oesophagus varices presents
a life threatening complication of liver cirrhosis. No effective method of
treatment is available until now, that would guarantee high grade of patient
wellness during the conditioning and investigation phase until the definitive
treatment could be introduced.
The fact that we have not found any report in the
literature about self-expandable metal stents (SEMS) application in acute
variceal bleeding had encouraged us to use stents usually used for oesophageal
malignancy and furthermore develop a special stent for this individual indication.
The aim of this study
was to evaluate the tissue response to oesophagus stent designed for stop
acute variceal bleeding in animal experiment in compare with another stent
used for iatrogenic treatment of different strictures of the oesophagus. Tissue
oxygen saturation (StO2) measurement was performed
before and after the implantation of the stents. Macroscopic and histological
investigations of the stented oesophagus segments were observed after 10 days.
calorimeter (DSC) is a well-established method for the demonstration of thermal
consequences of local and global conformational changes in biological systems,
but it has never been used for the investigation of the oesophagus. According
to our results the thermal denaturation of intact oesophagus, its mucosa and
muscle fragments revealed significant differences compared to healthy sample
in favour of the new stent.
Authors:M. Michalis, K.J. Finn, R. Podstawski, S. Gabnai, Á. Koller, A. Cziráki, M. Szántó, Z. Alföldi, and F. Ihász
Within recent years the popularity of sportive activities amongst older people, particularly competitive activities within certain age groups has increased. The purpose of this study was to assess the differences in the cardiorespiratory output at anaerobic threshold and at maximal power, output during an incremental exercise, among senior and young athletes. Ten elderly male subjects [mean (SD) age: 68.45 ± 9.32 years] and eight young male subjects [mean (SD) age: 25.87 ± 5.87 years] performed an incremental exercise test on a treadmill ergometer. No significant differences in body size were evident; however, the differences between the groups for peak power (451.62 ± 49 vs. 172.4 ± 32.2 W), aerobic capacity (57.97 ± 7.5 vs. 40.36 ± 8.6 mL kg−1 min−1), maximal heart rate (190.87 ± 9.2 vs. 158.5 ± 9.1 beats min−1), peak blood lactate (11 ± 1.7 vs. 7.3 ± 1.4 mmol L−1), and % VO2max at ventilatory thresholds (93.18 ± 4.3 vs. 79.29 ± 9.9%) were significantly lower in the senior athletes. The power output at anaerobic threshold was also higher (392 ± 48 vs. 151 ± 23 W) in the young athletes, explaining the significant difference in terms of performance between these groups. We have observed an evident deterioration in some of the cardiovascular parameters; however, the submaximal exercise economy seems to be preserved with aging. Exercise economy (i.e. metabolic cost of sustained submaximal exercise) was not different considerably with age in endurance-trained adults.