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Abstract
TG and DSC data were used to determine the thermal parameters of prednisone drug and tablets. Two formulations of prednisone 20 mg were analysed in the form of tablets. The TG curves of prednisone drug and tablets A and B displayed six, eight and seven thermal decomposition processes, respectively. Analysis of the DSC data pointed to chemical interactions between prednisone drug and the excipients of tablets A and B, suggested by alterations in the melting temperature of prednisone. The analysis revealed that prednisone drug is more stable than tablets A and B.
correlation between the Kitazawa rate constant and the thermal decomposition reaction rate constants. This correlation can be used to confirm pharmaceutical equivalence between reference and test products. There is an ongoing need to develop a better
's scholarship, by the Coordination for the Improvement of Higher Education Personnel (CAPES) through the Social Demand Program [88882.429856/2019-01] and institutional support through the Pharmaceutical Equivalence Center of the Nucleus of Quality Control of the
