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Orvosi Hetilap
Authors: Áron Cseh, Beáta Szebeni, Balázs Szalay and Barna Vásárhelyi

Manning, B. D., Cantley, L. C.: AKT/PKB signaling: navigating downstream. Cell, 2007, 129 , 1261–1274. Cantley L. C. AKT

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Physiology International
Authors: M. Nakamura, N. Satoh, H. Tsukada, T. Mizuno, W. Fujii, A. Suzuki, S. Horita, M. Nangaku and M. Suzuki

pathway may play an essential role in the pathogenesis of hypertension associated with metabolic syndrome ( 8, 9 ). Indeed, insulin enhances Na + transport through the insulin/Akt pathway in almost all nephron segments ( 10 ). For instance, in PTs

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regulation appear to be two signal transduction pathways: insulin-like growth factor-I/Akt/mammalian target of rapamycin (IGF-I/Akt/mTOR) and myostatin/Smad [ 1 ]. Increased protein synthesis induced by activation of the IGF-I/Akt/mTOR signal transduction

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interferes with adrenocorticotropin/3′,5′-cyclic adenosine monophosphate (cAMP) signaling, possibly through a Janus kinase 2-phosphatidylinositol 3-kinase/Akt-phosphodiesterase 3-cAMP pathway, to down-regulate cholesterol side-chain cleavage cytochrome P450

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). Among dozens of molecular mediators related to angiogenesis, protein kinase B (AKT) and extracellular signal-regulated kinase (ERK 1/2) signaling pathways are significant as they control proliferation and survival of endothelial cells. There are

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Acta Biologica Hungarica
Authors: Tamara Babic, Jelena Dinic, Sonja Stojkovic Buric, Stefan Hadzic, Milica Pesic, Dragica Radojkovic and Aleksandra Divac Rankov

tumor onset and progression in genetically defined mouse models expressing activated Akt . Clin. Cancer Res . 16 , 486 – 496 . 3. Asati , V. , Mahapatra , D. K. , Bharti

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Interventional Medicine and Applied Science
Authors: Igor Rabelo de França, Daniela Meneses-Santos, Gabriela Virginia Moreira, Fábio Bessa Lima, Carla Roberta de Oliveira Carvalho and Anderson Carlos Marçal

muscle, adipose tissue, and liver [ 16 , 17 ]. The phosphorylation of these substrates leads to the activation of several kinases, namely phosphatidylinositol 3-kinase (PI3K), which causes the activation of protein kinase B (PKB or Akt) through

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Interventional Medicine and Applied Science
Authors: Szaniszló Z. Jávor, K. Shanava, E. Hocsák, M. Kürthy, J. Lantos, B. Borsiczky, I. Takács, Sz. Horváth, B. Balatonyi, S. Ferencz, A. Ferencz, E. Rőth and Gy. Wéber

.V. Cohen J.M. Downey 2006 Endogenous adenosine protects preconditioned heart during early minutes of reperfusion by activating Akt Am J Physiol

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