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stem cell transplantation detected by multiplex PCR assay. J Med Virol. 2017; 89: 358–362. 9 Ljungman P, de la Camara R, Cordonnier C, et al. Management of CMV, HHV-6, HHV-7 and

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.A. Fischer 2008 Emerging viruses in transplantation: there is more to infection after transplant than CMV and EBV Transplantation 86 1327 1339

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cardiac transplantation and CMV infection in rats. Transplantation 79 , 17–22 (2005). Williams J. W. Mechanistic study of malononitrileamide FK778 in cardiac transplantation and CMV

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Abstract

Haemophagocytic lymphohistiocytosis (HLH) describes a rare, poorly recognised and under-diagnosed immunopathological syndrome whereby there is a highly stimulated yet ineffective multisystem inflammatory response [1]. I present the first case in English literature of Cytomegalovirus (CMV) associated HLH diagnosed by clinical and serological means, and the fourth case of CMV associated haemophagocytic lymphohistiocytosis in an immunocompetent adult, according to HLH-2004 diagnostic guidelines. I include a literature review of CMV associated HLH in adults and raise awareness of checking serum ferritin in patients who present with a sepsis like syndrome. Additionally, this article discusses the merits of HLH-2004 diagnostic work-up without bone marrow biopsy, using clinical and serological means only. I support the reclassification of HLH alongside the other hyperinflammatory syndromes of SIRS, sepsis, septic shock, and MODS to improve understanding and recognition.

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Woo, P. C., Lo, C. Y., Lo, S. K., Siau, H., Peiris, J. S., Wong, S. S., Luk, W. K., Chan, T. M., Lim, W. W., Yuen, K. Y.: Distinct genotypic distribution of cytomegalovirus (CMV) envelope glycoprotein in bone marrow and renal transplant recipients with

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Hungarian Medical Journal
Authors: Pankaj Jain, Ramesh Roop Rai, Harsh Udawat, Sandeep Nijhawan and Amit Mathur

Keates, J., Lagahee, S., Gilley, P. et al.: CMV enteritis causing segmental ischemia and massive intestinal hemorrhage. Gastrointest. Endosc., 2001, 53 , 355–359. Gilley P. CMV

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580 584 Aleksic, I., Bayalei, M. M., Schorn, B. és mtsai: Resection for CMV ileitis in a patient supported by a left-ventricular assist device. Thorac. Cardiovasc

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European Journal of Microbiology and Immunology
Authors: Cosme Alvarado-Esquivel, Ada A. Sandoval-Carrillo, Fernando Vazquez-Alaniz, José M. Salas-Pacheco, Jesús Hernández-Tinoco, Luis Francisco Sánchez-Anguiano and Elizabeth Irasema Antuna-Salcido

, Schmid DS , Cannon MJ : Cytomegalovirus seroconversion rates and risk factors: implications for congenital CMV . Rev Med Virol 20 , 311 – 326 ( 2010 ) 8. Kenneson

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Orvosi Hetilap
Authors: Tamás Kullmann, Tibor Kárász, Béla Gartner, Ákos Issekutz, Attila Oláh and István Rácz

A szerzők 21 éves colitis ulcerosás nőbeteg esetét mutatják be. Azathioprinkezelés mellett pancytopenia és szeptikus sokk lépett fel. A kórképet az immunszuppresszív kezelés mellett aktiválódott cytomegalovirus-fertőzéshez társuló haemophagocytosis szindrómával és szövődményesen kialakult lázas neutropeniával magyarázták. Parenteralis ganciclovir- és széles spektrumú antibiotikus és komplex intenzív osztályos kezelés mellett a beteg gyógyult. Orv. Hetil., 2013, 154(49), 1959–1961.

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580 – 584 . [19]. I. Aleksic M.M. Bayalei B. Schorn 1998 Resection for CMV ileitis in a patient supported by a left-ventricular assist device Thorac. Cardiovasc. Surg. 46 105 – 106 . [20]. G. J. Toogood P. H. Gillespie

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