The formation of benzynes derivatives from ortho-trimethylsilyl triflates using tetra-n-butylammonium fluoride (TBAF) as the benzyne-forming trigger was achieved in a straightforward flow reactor at room temperature. These benzynes were immediately trapped in Diels—Alder reactions to deliver the desired cycloadducts.
]. The imino Diels–Alder reaction, first explored by Povarov in 1960 [ 6 ], is one of the most important synthetic methodologies for the synthesis of six-membered nitrogen containing heterocycles. This type of Diels–Alder reaction between
Thermodynamic and kinetic studies on reversible liquid-phase Diels Alder reaction between maleic anhydride and 2-methyl furan
Dynamic modelling by thermal analysis
Abstract
The liquid phase reaction between maleic anhydride and 1-methyl-furan leads to an exothermic cycloaddition. The reaction enthalpy, the rate constant and the equilibrium constant are evaluated with good precision by a method of analysis using thermal data and a dynamic model based on physical properties. The mathematical models that are presented here in a simple way (first-order system) represent the reaction accurately and are useful for studying other reactions and even industrial processes.
.; Nakai, Y.; Ohara, N.; Yoda, H.; Takabe, K.; Tanaka, F.; Barbas, C. F. J. Am. Chem. Soc. 2005 , 128 , 734–735. In case of the Diels–Alder reaction, a direct comparison of the wall-coated versus the packed-bed approach results
dispersed catalyst heals the material and prevents further crack growth. A different approach is based on the incorporation of reversible cross-linking functionalities in the polymer backbone, such as Diels–Alder (DA) adducts. Wouters et al. [ 9
452 484 Wang, B. and Sutherland, I. O. (1997): Self-replication in a Diels-Alder reaction. Chem. Commun . 16 :1495-1496. Self-replication in a Diels-Alder
173 179 Wang, B. and Sutherland, I. O. (1997): Self-replication in a Diels-Alder reaction. Chem. Commun 16 :1495-1496. Self-replication in a Diels-Alder
) Modification of multi-walled carbon nanotubes by Diels-Alder and Sandmeyer reactions. J. Nanosci. Nanotechnol. 7 , 2795–2807. Kalman E. Modification of multi-walled carbon nanotubes by Diels-Alder
–6093 “Flow synthesis of annulated 5-aryl-substituted pyridines by tandem intramolecular inverse-electron-demand hetero-/retro-Diels–Alder reaction”R. E. Martin, * M. Lenz, T. Alzieu, J. D. Aebi, L. Forzy Tetrahedron Letters 2013 , 54 , 6703
species, via pyrolysis of alkanes to produce olefins which are subsequently aromatized by a Diels-Alder type reaction to form PAHs, is well known. For example Fairburn et al. examined the flash pyrolysis of n-hexadecane in a microreactor at temperatures
