: Detecting and visualizing emergingtrends and transient patterns in scientific literature . Journal of the American Society for Information Science and Technology 57 3 359 – 377 10.1002/asi.20317 .
mainly by internet and television, and they are not strictly controlled, so often they do not pass any safety and control tests [ 2 , 3 ]. The authorities have identified an emergingtrend where over-the-counter products, represented as dietary
The current state of the art of polymer synthesis in (microstructured) continuous-flow reactors is given, focusing on controlled/living polymerization methods that allow for precision polymer design. Emerging trends and the most notable developments are discussed. Especially, the field of multistep reactions and online monitoring are highlighted, which in combination may give access to fully automated high-throughput polymer synthesis reactors in the future.
Tinder is a very popular smartphone-based geolocated dating application. The goal of the present study was creating a short Problematic Tinder Use Scale (PTUS).
Griffiths’ () six-component model was implemented for covering all components of problematic Tinder use. Confirmatory factor analyses were carried out on a Tinder user sample (N = 430).
Both the 12- and the 6-item versions were tested. The 6-item unidimensional structure has appropriate reliability and factor structure. No salient demography-related differences were found. Users irrespectively to their relationship status have similar scores on PTUS.
Tinder users deserve the attention of scientific examination considering their large proportion among smartphone users. It is especially true considering the emerging trend of geolocated online dating applications.
Before PTUS, no prior scale has been created to measure problematic Tinder use. The PTUS is a suitable and reliable measure to assess problematic Tinder use.
Ketamine and esketamine have garnered interest in both psychiatric research and clinical practice for treatment-resistant depression (TRD). In this review, we examined registered trials investigating the therapeutic use of ketamine or esketamine for TRD, with the aim of characterizing emerging trends and knowledge gaps.
The ClinicalTrials.gov electronic registry and results database was queried from inception to February 5, 2022, adhering to elements of the PRISMA guideline, we evaluated trial eligibility in the qualitative synthesis. Data regarding study design, drug regimens, and measures were subsequently abstracted and descriptively analyzed.
The search returned 86 records, of which 56 trials were included in the final review. The number of trials investigating ketamine and esketamine for TRD increased since 2008, with higher peaks observed in 2015 (n = 9) and 2021 (n = 9). Most trials were Phase 2 (13, 23.2%) or Phase 3 (11, 19.6%), gathering preliminary data on efficacy and/or further data on safety and efficacy with variant dosing and pharmacological approaches. By and large, trials examined ketamine and esketamine as individual versus combination treatments (45% and 25%, respectively). The Montgomery-Asberg Depression Rating Scale (MADRS) was most commonly used to assess clinical outcomes (75%).
There are increasingly large-scale and late-phase trials of esketamine over ketamine for TRD, coupled with efforts to centralize evidence on these medications. Yet several trials do not assess patient characteristics that may affect treatment response, such as age, sex, and race. By understanding these design limitations, scientists and clinicians can avoid research waste and funding bodies can judiciously direct support towards high priority research.
Lohr: Factors affecting international demand and trade in organic food products, Economic Research Service, USDA, 2001
Minou Yussefi-Helga Willer: The World of Organic Agriculture 2005 — Statistics and EmergingTrends www