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evaluation tends to construct a more comprehensive evaluation system. This study aims to design a set of objective evaluation index system, which consistent with the subjective judgments, in order to provide the basis for awarding, based on empirical analysis

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National Research Foundation of Korea) to develop Kor-Factor (KF), a qualitative evaluation index for Korean domestic academic journals, which is based on the KCI database in 2007. However, KF was developed based on the data of 3 years that had not been

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Abstract  

In Open Access (OA) environment where article-based or author-based evaluation is important, a new evaluation system is needed to accommodate characteristics of Open Access Resources (OAR) and to overcome limitations of pre-existing evaluation systems such as journal-based evaluation. Primary and secondary evaluation factors were selected. Primary factors include hits and citations that constitutes composite index. Several secondary factors each for article and author evaluation were selected for normalization of the indexes. To validate superiority of newly developed normalized composite index systems compared to the monovariable index system, time-driven bias and power of discrimination were adopted. The results led to the conclusion that composite index proved to be a more stable index offsetting the negative effects from one element to another and normalization makes the composite index even more stable by controlling the bias from external elements.

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. ( 2007 ). Translated from ‘Research on Construction of Evaluation Indexes and Model of Organi zation Niche’ . Science & Technology Progress and Policy , 24 ( 7 ), 156 . Yang , Z

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Acta Chromatographica
Authors: Xiaoyan Zhang, Jie Liu, Wenbo Sun, Xiangchun Shen, Xiaojian Gong, Cong Wang, Yan Liang, and Wei Zhou

Abstract

Natural hemostatic compounds from Toddalia asiatica (Linn) Lam (T. asiatica) root bark had been investigated by a novel strategy, chemical fingerprint–pharmacokinetic–pharmacodynamic (CF–PK–PD) for the first time in this study. The extract sample of T. asiatica root bark was subdivided into petroleum ether (PE), ethyl acetate (EA) and n-butanol (n-B) sample by reagent extraction, EA sample showed significant hemostatic activity using prothrombin time (PT), activated partial thromboplastin time (APTT) and fibrinogen (FIB) as evaluation indexes from rat plasma of PK experiment in hemorrhagic rat model. CF analysis was adopted to assist us to discover six natural compounds from T. asiatica root bark in actual rat plasma after sample treatment by Ultra Performance Liquid Chromatography-Electrospray Ionization (UPLC-ESI) MS, there were only lomatin and 5-methoxy-8-hydroxy psoralen showing significant hemostatic effect (P < 0.05) mainly through endogenous coagulation pathway and fibrinolytic system. In PK–PD study, six compounds in EA sample exhibited relatively rapid absorption and slow elimination characteristics. The mean T max and t 1/2β of isopimpinellin and pimpinellin were 1.74 and 0.59 h, 5.31 and 6.89 h in rats. On the basis of Sigmoid–E max model, PK–PD related curves of FIB in hemorrhagic rat model after treatment of T. asiatica root bark were obtained. Predicted E max, EC 50 and k e0 of FIB under isopimpinellin were 4.87 mg/mL, 1.39 μg/mL and 0.81 1/h; predicted E max, EC 50 and k e0 of FIB under pimpinellin were 4.29 mg/mL, 2.47 μg/mL and 0.77 1/h. In conclusion, hemostatic compounds from T. asiatica root bark had been materialized, there were lomatin, isopimpinellin, pimpinellin and 5-methoxy-8-hydroxy psoralen at least as its main active substances through coagulation pathways and fibrinolytic system. CF–PK–PD method as a promising method was worthy of follow-up opening, application in pharmaceutical research.

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Scientometrics
Authors: Yuan Wang, Ruimin Ma, Tianhao Tang, Xia Liu, Ping Xie, Jianxin Wang, Jianxiang Liu, Haideng Zhou, and Siwei Zhang

. Construction of evaluation index system Both teaching and research play important roles in the development of a university. The ranking of U.S. News and World Report ( 2011 ) mainly focuses on the teaching situation of a university, which lacks the

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-010-0333-2 . European Commission ( 2012 ). Evidence base for research and innovation . http://ec.europa.eu/research/evaluations/index_en.cfm?pg=fp7-evidence . Garfield , E 1955 Citation

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Scientometrics
Authors: Chuanfu Chen, Yuan Yu, Qiong Tang, Kuei Chiu, Yan Rao, Xuan Huang, and Kai Sun

evaluate online resources. Authority generally relates to expertise, recognition of official status of a source, and the reputation of the author and publisher. Authority has always been a high-priority and key evaluating index (Miller 1996 ; Smith

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): Plant Production Products. European Commission, Directorate-General Health and Consumers, Brussels, Belgium. ( http://ec.europa.eu/food/plant/protection/evaluation/index_en.htm ) Plant

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When anyone aims at evaluating clustering results, or even comparing clustering methods, he will be faced with the problem of the choice of reliable clustering quality indexes. The classical evaluation indexes for the clustering quality are based on the

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