evaluation tends to construct a more comprehensive evaluation system. This study aims to design a set of objective evaluationindex system, which consistent with the subjective judgments, in order to provide the basis for awarding, based on empirical analysis
Authors:Young Man Ko, Soo-Ryun Cho, and Yong Seok Park
National Research Foundation of Korea) to develop Kor-Factor (KF), a qualitative evaluationindex for Korean domestic academic journals, which is based on the KCI database in 2007. However, KF was developed based on the data of 3 years that had not been
In Open Access (OA) environment where article-based or author-based evaluation is important, a new evaluation system is needed
to accommodate characteristics of Open Access Resources (OAR) and to overcome limitations of pre-existing evaluation systems
such as journal-based evaluation.
Primary and secondary evaluation factors were selected. Primary factors include hits and citations that constitutes composite
index. Several secondary factors each for article and author evaluation were selected for normalization of the indexes.
To validate superiority of newly developed normalized composite index systems compared to the monovariable index system, time-driven
bias and power of discrimination were adopted.
The results led to the conclusion that composite index proved to be a more stable index offsetting the negative effects from
one element to another and normalization makes the composite index even more stable by controlling the bias from external
Authors:Xiaoyan Zhang, Jie Liu, Wenbo Sun, Xiangchun Shen, Xiaojian Gong, Cong Wang, Yan Liang, and Wei Zhou
Natural hemostatic compounds from Toddalia asiatica (Linn) Lam (T. asiatica) root bark had been investigated by a novel strategy, chemical fingerprint–pharmacokinetic–pharmacodynamic (CF–PK–PD) for the first time in this study. The extract sample of T. asiatica root bark was subdivided into petroleum ether (PE), ethyl acetate (EA) and n-butanol (n-B) sample by reagent extraction, EA sample showed significant hemostatic activity using prothrombin time (PT), activated partial thromboplastin time (APTT) and fibrinogen (FIB) as evaluation indexes from rat plasma of PK experiment in hemorrhagic rat model. CF analysis was adopted to assist us to discover six natural compounds from T. asiatica root bark in actual rat plasma after sample treatment by Ultra Performance Liquid Chromatography-Electrospray Ionization (UPLC-ESI) MS, there were only lomatin and 5-methoxy-8-hydroxy psoralen showing significant hemostatic effect (P < 0.05) mainly through endogenous coagulation pathway and fibrinolytic system. In PK–PD study, six compounds in EA sample exhibited relatively rapid absorption and slow elimination characteristics. The mean Tmax and t1/2β of isopimpinellin and pimpinellin were 1.74 and 0.59 h, 5.31 and 6.89 h in rats. On the basis of Sigmoid–Emax model, PK–PD related curves of FIB in hemorrhagic rat model after treatment of T. asiatica root bark were obtained. Predicted Emax, EC50 and ke0 of FIB under isopimpinellin were 4.87 mg/mL, 1.39 μg/mL and 0.81 1/h; predicted Emax, EC50 and ke0 of FIB under pimpinellin were 4.29 mg/mL, 2.47 μg/mL and 0.77 1/h. In conclusion, hemostatic compounds from T. asiatica root bark had been materialized, there were lomatin, isopimpinellin, pimpinellin and 5-methoxy-8-hydroxy psoralen at least as its main active substances through coagulation pathways and fibrinolytic system. CF–PK–PD method as a promising method was worthy of follow-up opening, application in pharmaceutical research.
Construction of evaluationindex system
Both teaching and research play important roles in the development of a university. The ranking of U.S. News and World Report ( 2011 ) mainly focuses on the teaching situation of a university, which lacks the
Authors:Chuanfu Chen, Yuan Yu, Qiong Tang, Kuei Chiu, Yan Rao, Xuan Huang, and Kai Sun
evaluate online resources.
Authority generally relates to expertise, recognition of official status of a source, and the reputation of the author and publisher. Authority has always been a high-priority and key evaluatingindex (Miller 1996 ; Smith
When anyone aims at evaluating clustering results, or even comparing clustering methods, he will be faced with the problem of the choice of reliable clustering quality indexes. The classical evaluationindexes for the clustering quality are based on the