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Abstract  

In advanced methods of delineation and mapping of scientific fields, hybrid methods open a promising path to the capitalisation of advantages of approaches based on words and citations. One way to validate the hybrid approaches is to work in cooperation with experts of the fields under scrutiny. We report here an experiment in the field of genomics, where a corpus of documents has been built by a hybrid citation-lexical method, and then clustered into research themes. Experts of the field were associated in the various stages of the process: lexical queries for building the initial set of documents, the seed; citation-based extension aiming at reducing silence; final clustering to identify noise and allow discussion on border areas. The analysis of experts’ advices show a high level of validation of the process, which combines a high-precision and low-recall seed, obtained by journal and lexical queries, and a citation-based extension enhancing the recall. This findings on the genomics field suggest that hybrid methods can efficiently retrieve a corpus of relevant literature, even in complex and emerging fields.

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., Yu, J., Hood, L.: Prostate cancer expression profiling by cDNA sequencing analysis. Genomics 59 , 178-186 (1999). Prostate cancer expression profiling by cDNA sequencing analysis Genomics

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Acta Biologica Hungarica
Authors: A. Mádi, Tünde Pusztahelyi, Mária Punyiczki, and L. Fésüs

: towards functional genomics of microbial pathogens. Mol. Microbiol. 33 , 1103-1117. Comparative proteome analysis of Mycobacterium tuberculosis and Mycobacterium bovis BCG strains: towards functional genomics of microbial

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First decade of post-genomic era. Hopes, disappointments, new answers

Remények, csalódások, újszerű válaszok

Orvosi Hetilap
Author: György Kosztolányi

. E., Collins, F. S.: Genomic medicine – a primer. New Engl. J. Med., 2002, 347 , 1512–1520. Collins F. S. Genomic medicine – a primer New Engl. J

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Th. ponticum using genomic in situ hybridization. Genome 141 :580–586. Thomas J.B. Genome analysis of Thinopyrum intermedium and Th. ponticum using genomic in situ

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Oyama, M. A. and Chittur, S. (2005): Genomic expression patterns of cardiac tissues from dogs with dilated cardiomyopathy. Am. J. Vet. Res. 66 , 1140–1155. Chittur S. Genomic

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Haig, D. (2000b): Genomic imprinting, sex biased dispersal, and social behavior. In LeCroy, D. and Moller, P. (eds): Evolutionary Perspectives on Human Reproductive Behavior. Annals of the New York Academy of

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) Detection of rye DNA in wheat-rye hybrids and wheat translocation stocks using total genomic DNA as a probe. Plant. Mol. Biol. Rep. 7 , 150–158. Miki B. Detection of rye DNA in wheat

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Boyd, D. A., Peters, G. A., Ng, L. K. and Mulvey, M. R. (2000): Partial characterization of a genomic island associated with the multidrug resistance region of Salmonella enterica Typhimurium DT104. FEMS Microbiol. Lett. 189 , 285

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