Authors:Gabriella Pár, Áron Vincze, Timea Berki, Attila Miseta, László Kereskai, László Pajor, Angela Oszter, Ferenc Jakab, Zoltán Szereday, Ágnes Nagy, Béla Hunyady and Alajos Pár
transient elastography (FibroScan) in chronic HCVinfection Abstract Z. Gastroenterol. 48 611 .
. J. Stebbing L. Farouk G. Pano M. Anderson L. R. Jiao S. Mandalia M. Bower B. Gazzard M. Nelson 2010 A meta
Authors:Nimzing G. Ladep, Oche O. Agbaji, Patricia A. Agaba, Muazu A. Mohammed, Godwin E. Imade and John A. Idoko
To determine the relationship between the immunological status and anti-HCV detection of HIV-1 infected individuals in an HIV/AIDS cohort within an African population.
Retrospective study of randomly selected HIV/AIDS patients.
The biodata of 1044 consenting HIV infected patients were analyzed retrospectively. These patients had been enrolled following the confirmation of their HIV status by western blot assay after an initial reactive ELISA. Blood obtained from the patients were subjected to serological tests to determine their anti-HCV antibody status using third generation Enzyme Immunoassay (DIA.PRO Diagnostic, Bioprobes srl, Italy). CD4 count was done by flow cytometry (Partec Cyflow, Germany) and viral load by PCR (Roche Amplicor 1.50). The data were analyzed using the Epi Info 2004 statistical software.
Ninety out of 1044 patients (8.6%) were positive for anti-HCV antibodies. The rate of HCV infection was directly proportional to the CD4+ group (6.8% vs. 15.4% for < 201 and > 800, respectively,
There is an associated higher chance of detecting anti-HCV in sera of the HIV-1 infected patients whose immunological status are better compared to severely immunocompromised ones.
S. Feng 2006 Long-term histological effects of preemptive antiviral therapy in liver transplant recipients with hepatitis C virus (HCV) infection Hepatology 44 4Suppl.1 3 .
. M. F. Abdelmalek R. J. Firpi C. Soldevila