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been identified in Enterobacterales relating to 3 classes of β-lactamases: the Ambler class A, B, and D [ 2 ]. Class D enzymes of the OXA-48 type carbapenemase was first described in a Klebsiella pneumoniae strain from Turkey [ 3 ]. After then, OXA

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enzymes include class A carbapenemases like Klebsiella pneumoniae carbapenemase (KPC), class B carbapenemases like Verona integron-encoded metallo-beta-lactamase, New Delhi metallo-beta-lactamase (NDM-1), imipenemase, and class D oxacillinases like OXA

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Abstract  

Oxamniquine (OXA) is a schistosomicide agent that causes some adverse effects in central nervous system. Intending to improve OXA therapeutic properties, a polymeric prodrug was designed. Currently, there is an increasing interest of thermal analytical techniques in the pharmaceutical area, so differential thermal analysis (DTA) and thermogravimetry (TG) were carried out to evaluate the thermal behavior of OXA, polymethacrylic acid (PMA), [poly(methacrylic-co-oxamniquine methacrylate)acid] (PMOXA) and physical mixture (OXA+PMA). The thermoanalytical profile of the physical mixture showed characteristic events of the thermal decomposition of OXA and PMA. Distinctly, PMOXA DTA curve did not show an endothermic peak at 148.5C indicating that the drug was incorporated into the polymeric system. These results were corroborated by the IR spectroscopy and X-ray diffraction data.

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Acta Microbiologica et Immunologica Hungarica
Authors: Elham Abbasi, Hossein Goudarzi, Ali Hashemi, Alireza Salimi Chirani, Abdollah Ardebili, Mehdi Goudarzi, Javad Yasbolaghi Sharahi, Sara Davoudabadi, Ghazaleh Talebi, and Narjes Bostanghadiri

compromise their efficacy [ 5 ]. The most significant carbapenem resistance mechanism in A. baumannii has been attributed mainly to chromosome and plasmid -encoded carbapenemases, such as OXA carbapenemases and metallo-β-lactamases (MBLs) [ 6 ]. In addition

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carbapenem-resistant mechanisms. The CHDLs (OXA carbapenemases) of Acinetobacter spp. have five phylogenetic subgroups: bla OXA-51 like , bla OXA-58 like , bla OXA-23 like , bla OXA-24/40 like , and bla OXA-143 like [ 3–9 ]. The bla OXA-51 like gene

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Journal of Radioanalytical and Nuclear Chemistry
Authors: N. St. Kalmykov, A. Arhipov, A. Abramov, N. Ivanova, B. Iofa, O. Pronina, Yu. Sapozhnikov, and A. Anisimov

Abstract  

Liquid-liquid extraction of several cations by some oxa-tia- and tia-crown ethers was studied. Sr(II), Pb(II) and Ag(I) were taken as hard, borderline and soft Lewis acids, respectively. Trace amounts of210Sr and110mAg were used as chemical yield monitors. The results were explained by the Pearson theory. Some of the examined compounds posses high affinity towards Ag(I) and Pb(II) extraction. The distribution coefficent for Ag(I) reached the value of 140.

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[ 9 ]. At present, oxacillinases are encoded by five different subclasses of bla oxa in A. baumannii strains. The bla oxa-51 is documented to be associated with intrinsic resistant with 70 variants. Few acquired genes are also reported

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Abstract  

To simplify TRPO process, a novel ligand, N,N’-dimethyl-3-oxa-glutaramic acid (DMOGA), was synthesized and used for stripping of An(III, IV) from 30% TRPO-kerosene. The distribution ratios for transuranium elements, including Np(IV), Pu(IV), Am(III), and some fission products, including Eu(III), Fe and Zr between 30% TRPO-kerosene and various HNO3-DMOGA solutions were measured. An(III, IV) and Ln(III) extracted to TRPO from simulated high level liquid waste could be recovered with an efficiency of 99.9% above in one stream with a 3-stage crosscurrent strip experiment with 0.2M DMOGA in HNO3 solution. Using this new agent, the back extraction of TRU elements from loaded TRPO phase becomes more simple and practical. Therefore, the original TRPO process could be simplified.

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Acta Microbiologica et Immunologica Hungarica
Authors: Márió Gajdács, Marianna Ábrók, Andrea Lázár, Laura Jánvári, Ákos Tóth, Gabriella Terhes, and Katalin Burián

, SFO, SFC and IBC), Class D (e.g. OXA-23 group, OXA-48-group) and Class B (e.g. VIM, GIM, SIM, NDM, IMP, IND, AIM, DIM and SPM) enzymes; while the first two groups consist of serine-β-lactamases, the members of the latter group are exclusively metallo

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carbapenemases (OXA-23, OXA-24/40, OXA-58, and OXA-143) [ 3 ]. Class B (SPM, GIM, IMP, VIM, and NDM) and class A (GES-14) carbapenemases are less frequently detected in this microorganism [ 4, 5 ]. On the other hand, resistance to third generation cephalosporins

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