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Authors: Yonca B. Kabak, Mahmut Sozmen, Alparslan K. Devrim, Mert Sudagidan, Funda Yildirim, Tolga Guvenc, Murat Yarim, Yavuz M. Gulbahar, Ishtiaq Ahmed, Efe Karaca and Sinem Inal

it contributes to tumour progression and invasiveness in more advanced diseases ( Akhurst and Derynck, 2001 ). Platelet-derived growth factor (PDGF) is a 30 kDa dimeric molecule, composed of two disulphide-linked polypeptide chains designated as A and

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parenchyma and in the plexiform lesions. The expression of platelet-derived growth factor (PDGF) and PDGF receptor was elevated in explanted lungs of patients with severe PAH [ 6 ], and the appearance of vascular endothelial growth factor (VEGF) and VEGF

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Authors: Zoltán Mátrai, Gabriella Liszkay, Vanda Plotár, Zsolt Orosz, Judit Székely, Erika Hitre, Alexandra Bartal, Zoltán Langmár, Katalin Bőcs, Ferenc Rényi Vámos, Ákos Sávolt and László Tóth

(PDGF) B-chain fusion gene generates a transforming protein that is processed to functional PDGF-BB. Cancer Res., 1999, 59 , 3719–3723. Sjoblom T. The dermatofibrosarcoma

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Authors: Miklós Petrás, Gábor Hutóczki, Imre Varga, György Vereb, János Szöllősi, László Bognár, Péter Ruszthi, Annamária Kenyeres, Judit Tóth, Zoltán Hanzély, Beáta Scholtz and Álmos Klekner

1993 Effects of EGF, bFGF, NGF and PDGF (bb) on cell proliferative, migratory and invasive capacities on human brain-tumour biopsies in vitro Int J Cancer 53 209 214

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. L., Bishop, J. M. (1995) b PDGF receptor mutants defective for mitogenesis promote neurite outgrowth in PC12 cells. Curr. Biol. 5 , 168-178. b PDGF receptor mutants defective for mitogenesis promote neurite outgrowth in PC

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Nakamura, N., Shino, K., Natsumme, T. és mtsai: Early biological effect of in vivo gene transfer of platelet derived growth factor (PDGF) into healing patellar ligament. Gene Ther., 1998, 5 , 1165

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Authors: Krisztina Fischer, Orsolya Galamb, Béla Molnár, Zsolt Tulassay and András Szabó

Eitner, F., Ostendorf, T., Kretzler, M. és mtsai: ERCB-Consortium. PDGF-C expression in the developing and normal adult human kidney and in glomerular diseases. J. Am. Soc. Nephrol., 2003, 14 , 1145

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, C. , Frangos , J. A. ( 1999 ) Temporal gradient in shear but not steady shear stress induces PDGF-A and MCP-1 expression in endothelial cells: role of NO, NFKB and egr-1 . Arterioscler. Thromb. Vasc. Biol. 19 , 996 – 1003

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Authors: Ildikó Bódi, Krisztina H.-Minkó, Zsolt Prodán, Nándor Nagy and Imre Oláh

; 109: 954–960. 39 Morrison-Graham K, Schatteman GC, Bork T, et al. A PDGF receptor mutation in the mouse (Patch) perturbs the development of a non-neuronal subset of neural

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Hepatology 30 4 977 – 986 . 23. M. Pinzani 2002 PDGF and signal transduction in hepatic stellate

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