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Introduction Recent years have seen stem cell research rising to the forefront of biomedical science, public health and research policy (Department of Health and Human Services 2001 , 2006 ). “A stem cell is a special

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Abstract  

Honour Index (HoI), a method to evaluate research performance within different research fields, was derived from the impact factor (IF). It can be used to rate and compare different categories of journals. HoI was used in this study to determine the scientific productivity of stem cell research in the Asian Four Dragons (Hong Kong, Singapore, South Korea and Taiwan) from 1981 to 2001. The methodology applied in this study represents a synthesis of universal indicator studies and bibliometric analyses of subfields at the micro-level. We discuss several comparisons, and conclude the developmental trend in stem cell research for two decades.

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Abstract  

In this study, we aim to evaluate the global scientific production of stem cell research for the past 16 years and provide insights into the characteristics of the stem cell research activities and identify patterns, tendencies, or regularities that may exist in the papers. Data are based on the online version of SCI, Web of Science from 1991 to 2006. Articles referring to stem cell were assessed by many aspects including exponential fitting the trend of publication outputs during 1991–2006, distribution of source title, author keyword, and keyword plus analysis. Based on the exponential fitting the yearly publicans of the last decade, it can also be calculated that, in 2,011, the number of scientific papers on the topic of stem-cell will be twice of the number of publications in 2006. Synthetically analyzing three kinds of keywords, it can be concluded that application of stem cell transplantation technology to human disease therapy, especially research related on “embryonic stem cell” and “mesenchymal stem cell” is the orientation of all the stem cell research in the 21st century. This new bibliometric method can help relevant researchers realize the panorama of global stem cell research, and establish the further research direction.

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, on up to plagiarism by referees, has sometimes been suspected. About a year ago, a group of people working on the kind of stem cell research that involves reprogramming skin or other cells to act like early embryonic ones drafted a new kind of

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A kéz idegsérüléseinek helyreállító műtétei után napjainkban a végeredmények korántsem mondhatók egyértelműen kedvezőknek. Úgy tűnik, hogy e sérülések magas szintű rekonstrukciós lehetőségeinek végső határához érkeztünk, ezért nem véletlen, hogy évek óta folynak – jelenleg legnagyobbrészt kísérletes – kutatások az eredmények javítására. Ennek egyik módszere a sejtkultúrában kezelt pluripotens mesenchymalis őssejtek, szövetindukáló polipeptidek (növekedési faktorok) és a fenti sejtek megtapadására szolgáló vázszerkezetek együttes felhasználása (úgynevezett tissue engineering) az új idegszövet kialakítása céljából. Az új szövetféleség létrejöttének feltételei géntechnikával tovább javíthatók. A szerző dolgozatában összefoglalja az újabb irodalmi adatok alapján a módszer idegsérülésekre vonatkozó kísérletes alapjait, alkalmazásának lehetőségeit és utal az eljárás lehetséges klinikai felhasználására. Megállapítja, hogy bár a jövő útja minden bizonnyal az őssejtek szélesebb körű felhasználása felé vezet, mindaddig, amíg a klinikai gyakorlat számára egyértelműen kedvezőbb tapasztalatok nem állnak rendelkezésre, a jelenleg ismert és bevált műtéti és utókezelési módszerek magas szintű kivitelezése szükséges. Orv. Hetil., 2013, 154, 574–580.

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Abstract  

The case of Dr. Hwang Woo Suk, the South Korean stem-cell researcher, is arguably the highest profile case in the history of research misconduct. The discovery of Dr. Hwang’s fraud led to fierce criticism of the peer review process (at Science). To find answers to the question of why the journal peer review system did not detect scientific misconduct (falsification or fabrication of data) not only in the Hwang case but also in many other cases, an overview is needed of the criteria that editors and referees normally consider when reviewing a manuscript. Do they at all look for signs of scientific misconduct when reviewing a manuscript? We conducted a quantitative content analysis of 46 research studies that examined editors’ and referees’ criteria for the assessment of manuscripts and their grounds for accepting or rejecting manuscripts. The total of 572 criteria and reasons from the 46 studies could be assigned to nine main areas: (1) ‘relevance of contribution,’ (2) ‘writing / presentation,’ (3) ‘design / conception,’ (4) ‘method / statistics,’ (5) ‘discussion of results,’ (6) ‘reference to the literature and documentation,’ (7) ‘theory,’ (8) ‘author’s reputation / institutional affiliation,’ and (9) ‘ethics.’ None of the criteria or reasons that were assigned to the nine main areas refers to or is related to possible falsification or fabrication of data. In a second step, the study examined what main areas take on high and low significance for editors and referees in manuscript assessment. The main areas that are clearly related to the quality of the research underlying a manuscript emerged in the analysis frequently as important: ‘theory,’ ‘design / conception’ and ‘discussion of results.’

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Solter, D.: From teratocarcinomas to embryonic stem cells and beyond: a history of embryonic stem cell research. Nat. Rev. Genet., 2006, 7 , 319–327. Solter D. From teratocarcinomas

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-restricted stem cells line which have continuous in vitro proliferative capacity and strong differentiation potential from human embryonic and fetal germ cells. Afterwards, stem cells research was quickly pushed to a new high. Science weekly considered it the most

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Orvosi Hetilap
Authors: Zsolt Matula, Gyöngyi Kudlik, Veronika Urbán S., and Ferenc Uher

., Endele, M., Schroeder, T.: Quantitative single-cell approaches to stem cell research. Cell Stem Cell, 2014, 15 (5), 546–558. 13 Macaulay, I. C., Voet, T

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Scientometrics
Authors: Cathelijn J. F. Waaijer, Cornelis A. van Bochove, and Nees Jan van Eck

misconduct’, ‘validity’, ‘replication’, ‘integrity’, ‘ethics’). Although the clusters on space and physics and on stem cell research are located more towards the edges of the map, they do have locations close to areas one would expect them to be

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