Search Results

You are looking at 1 - 10 of 53 items for :

  • "UPLC–MS/MS" x
  • Refine by Access: All Content x
Clear All
Acta Chromatographica
Authors: Yongxi Jin, Yuyan Chen, Jiawen Liu, Xi Bao, Yinghao Zhi, Congcong Wen, and Wenzong Zhu

–tandem mass spectrometry (UPLC–MS/MS) reported for the determination of ebeiedinone. To the best of our knowledge, the pharmacokinetics of ebeiedinone had not been reported. In this paper, UPLC–MS/MS method was established to determine ebeiedinone in mouse

Open access
Acta Chromatographica
Authors: Yunfang Zhou, Bingbao Chen, Junyan Chen, Yanwen Dong, Shuanghu Wang, Congcong Wen, Xianqin Wang, and Xiaomin Yu

pH using the mixture of acetonitrile and 0.1% formic acid (45:55, v / v ) as a mobile phase. The analytical run time was 3.5 min. In this paper, an ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) method with an

Open access
Acta Chromatographica
Authors: Haiya Wu, Mengrou Lu, Jiamin He, Miaoling Huang, Aote Zheng, Meiling Zhang, Congcong Wen, and Jufen Ye

chromatography–tandem mass spectrometer (LC–MS/MS), ultra-performance LC–MS/MS (UPLC–MS/MS) has higher detection sensitivity with more powerful separation and analytical capability, which are essential for studying Chinese medicine with complex contents and the

Open access
Acta Chromatographica
Authors: Aixia Han, Guanyang Lin, Jinzhang Cai, Qing Wu, Peiwu Geng, Jianshe Ma, Xianqin Wang, and Chongliang Lin

reported the pharmacokinetics of hirsutine and hirsuteine. Wu et al. [ 15 ] established an ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) method to simultaneously measure rhynchophylline and hirsutine in rat plasma and also

Open access
Acta Chromatographica
Authors: Qinghua Weng, Lianguo Chen, Luxin Ye, Xiaojie Lu, Zheng Yu, Congcong Wen, Yichuan Chen, and Gang Huang

reported. Compared with capillary-zone electrophoresis, HPLC, and LC–MS, an ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) method was more sensitive, high throughput, and time saving [ 16 – 20 ]. In this study

Open access

long runtime, and the selective ion monitoring (SIM) mode was used to quantify isocorynoxeine in rat plasma in their study. In this study, we presented a fast and sensitive UPLC–MS/MS method for isocorynoxeine in rat plasma in the multiple

Open access
Acta Chromatographica
Authors: Jianbo Li, Zheng Yu, Cheng Han, Zhening Wang, Yujie Hu, Congcong Wen, and Chongliang Lin

, distribution, and metabolism, and the bioavailability was greatly improved. Ultra-high performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) combined technology combines the high resolution of liquid chromatography with the high

Open access
Acta Chromatographica
Authors: Quan Zhou, Zhiguang Zhang, Peiwu Geng, Bingge Huang, Xianqin Wang, and Xiaomin Yu

isocratic mobile phase consisting of acetonitrile–water–formic acid (75:25:0.1, v / v ). The ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) method that we developed focused on the analytical ability for ligustroflavone in rat

Open access
Acta Chromatographica
Authors: Peiwu Geng, Jing Zhang, Bingbao Chen, Qianqian Wang, Shuanghu Wang, and Congcong Wen

conventional analytical techniques, ultra-performance liquid chromatography coupled with tandem mass spectrometry (UPLC–MS/MS) is documented to possess improved sensitivity, selectivity, and specificity in quantitative determination of the active compound of

Open access
Acta Chromatographica
Authors: Xi Bao, Bingge Huang, Yiting Mao, Zhiguang Zhang, Yunfang Zhou, Congcong Wen, and Quan Zhou

has been published. Here, a rapid and simple UPLC–MS/MS method was established for determination of byakangelicol in rat plasma. The pharmacokinetics of byakangelicol after oral (PO) and intravenous (IV) administration was studied

Open access