Search Results

You are looking at 1 - 10 of 22 items for :

  • "addiction vulnerability" x
  • Refine by Access: All Content x
Clear All

J. R. Taylor M. N. Potenza 2003 Developmental neurocircuitry of motivation in adolescence: A critical period of addiction vulnerability

Open access
Journal of Behavioral Addictions
Authors:
Yihong Zhao
,
Martin Paulus
,
Kara S. Bagot
,
R. Todd Constable
,
H. Klar Yaggi
,
Nancy S. Redeker
, and
Marc N. Potenza

Abstract

Background and Aims

Screen media activity (SMA) may impact neurodevelopment in youth. Cross-sectionally, SMA has been linked to brain structural patterns including cortical thinning in children. However, it remains unclear whether specific brain structural co-variation patterns are related to SMA and other clinically relevant measures such as psychopathology, cognition and sleep in children.

Methods

Adolescent Brain Cognitive Development (ABCD) participants with useable baseline structural imaging (N = 10,691; 5,107 girls) were analyzed. We first used the Joint and Individual Variation Explained (JIVE) approach to identify cortical and subcortical covariation pattern(s) among a set of 221 brain features (i.e., surface area, thickness, or cortical and subcortical gray matter (GM) volumes). Then, the identified structural covariation pattern was used as a predictor in linear mixed-effect models to investigate its associations with SMA, psychopathology, and cognitive and sleep measures.

Results

A thalamus-prefrontal cortex (PFC)-brainstem structural co-variation pattern (circuit) was identified. The pattern suggests brainstem and bilateral thalamus proper GM volumes covary more strongly with GM volume and/or surface area in bilateral superior frontal gyral, rostral middle frontal, inferior parietal, and inferior temporal regions. This covariation pattern highly resembled one previously linked to alcohol use initiation prior to adulthood and was consistent in girls and boys. Subsequent regression analyses showed that this co-variation pattern associated with SMA (β = 0.107, P = 0.002) and externalizing psychopathology (β = 0.117, P = 0.002), respectively.

Discussion and Conclusions

Findings linking SMA-related structural covariation to externalizing psychopathology in youth resonate with prior studies of alcohol-use initiation and suggest a potential neurodevelopmental mechanism underlying addiction vulnerability.

Open access

-making in youth: Relationships to addiction vulnerability . Journal of Behavioral Addictions , 2 ( 1 ), 1 – 9 . Barrett , D. ( 2010 ). Supernormal stimuli: How primal urges

Open access

impulsivity followed by neurodevelopmental differences seems to underlie the addiction vulnerability in adolescence, it would also lead adolescents to fall easily into Internet gaming ( Chambers, Taylor, & Potenza, 2003 ). In this study, we aimed to identify

Open access

Ten myths (or facts?) about workaholism: An appetitive motivation framework

Commentary on: Ten myths about work addiction (Griffiths et al., 2018)

Journal of Behavioral Addictions
Author:
Steve Sussman

free time. It is then easier to infer operation of individual difference factors. As with other levels of analysis, personality may reflect common, overlapping features of addiction vulnerability (e.g., reward deficiency-related) as well as specific

Open access

addiction vulnerability. Chapter 12 by Nader et al. summarizes the effect of certain environmental and internal factors on addiction more precisely on cocaine use. They review results coming from brain imaging studies suggesting for example a

Open access

of addiction vulnerability and chronicity; whereas other aspects (such as habit and compulsivity) were hypothesized to be relatively unimportant for vulnerability ( Yucel et al., 2019 ). Understanding of gambling “subtypes” and how to classify people

Open access

. A. , Taylor , J. R. , & Potenza , M. N. ( 2003 ). Developmental neurocircuitry of motivation in adolescence: A critical period of addiction vulnerability . American Journal of Psychiatry, 160 ( 6

Open access
Journal of Behavioral Addictions
Authors:
Skyler Sklenarik
,
Marc N. Potenza
,
Mateusz Gola
,
Ariel Kor
,
Shane W. Kraus
, and
Robert S. Astur

. A. , Taylor , J. R. , & Potenza , M. N. ( 2003 ). Developmental neurocircuitry of motivation in adolescence: A critical period of addiction vulnerability . American Journal of Psychiatry, 160 ( 6

Open access

. , Mayes , L. C. , & Potenza , M. N. ( 2013 ). Risk-taking and decision-making in youth: Relationships to addiction vulnerability . Journal of

Open access