The IMPACT-II Investigators:
Randomised placebo-controlled trial of effect of eptifibatide on complications of percutaneous coronary intervention: IMPACT II. Integrilin to Minimise Platelet Aggregation and Coronary Thrombosis-II. Lancet, 1997,
Authors:Boglárka Vincze, Márta Varga, Orsolya Kutasi, Petra Zenke, Ottó Szenci, Ferenc Baska, Alan Bartels, Sándor Spisák, Sándor Cseh, and Norbert Solymosi
independence of the EGS condition, Fisher's exact test was used ( Agresti, 2007 ). The confidence interval of prevalence was estimated by Wilson's method ( Agresti and Coull, 1998 ). The family aggregation was studied by genealogical index analysis ( Hill, 1980
Electrophoretic assay is proposed as a control method for the cationic aggregation in chromium complexes. The experimental
agreement between the physico-chemical characteristics of the non-dialyzable fraction, and the absence of electrophoretic
mobility, indicate the validity of this approach. Furthermore, the experimental experience in animal distribution studies
corroborates the usefulness of the method.
A major difficulty with bibliometric measures of departmental research contributions based upon publications counts has concerned the summing of publications of different types. An attempt is made in this paper to bypass this aggregation problem by appeal to the methods of Data Envelopment Analysis (DEA). In this way we investigate the technical efficiency of UK university departments of economics as producers of research. The data set used is an extended version of the one which informed the recent Universities Funding Council peer review, and the results obtained here are compared with those obtained by the Council. We conclude that, although due caution is needed in the interpretation of results, DEA has a positive contribution to make in the development of meaningful indicators of university performance.
Authors:X. Cao, X. Yang, J. Shi, Y. Liu, and C. Wang
The effect of glucose (0–15 mass%) on the kinetics of bovine serum albumin (BSA) denatured aggregation at high concentration
in aqueous solution has been studied by differential scanning calorimetry. The observed denatured aggregation process was
irreversible and could be characterized by a denaturation temperature (Tm), apparent activation energy (Ea), the approximate order of reaction, and pre-exponential factor (A). As the glucose concentration increased from 0 to 15 mass%, Tm increased, Ea also increased from 514.59409±6.61489 to 548.48611±7.81302 kJ mol−1, and A/s−1 increased from 1.24239E79 to 5.59975E83. The stabilization increased with an increasing concentration of glucose, which was
attributed to its ability to alter protein denatured aggregation kinetics.
The kinetic analysis was carried out using a composite procedure involving the iso-conversional method and the master plots
method. The iso-conversional method indicated that denatured aggregation of BSA in the presence and absence of glucose should
conform to single reaction model. The master plots method suggested that the simple order reaction model best describe the
process. This study shows the combination of iso-conversional method and the master plots method can be used to quantitatively
model the denatured aggregation mechanism of the BSA in the presence and absence of glucose.
Authors:E. T. Stepkowska, S. Yariv, J. L. Pérez-Rodríguez, A. Justo, A. Ruiz-Conde, and P. Sánchez-Soto
A dredged sludge was studied to investigate the influence of ageing and of pretreatment on its drying rate, water sorption/retention, thermal mass loss, XRD and microstructure (SEM).
Ageing caused change in particle thickness and specific surface, a gradual aggregation to form units of the size 10–50 μm, formation of macropores of similar size, unhomogeneity and fissures between aggregates and “super-aggregates”. Macropores were detectable by the initial drying rate especially at 45°C. They indicated a tendency of collapsing at a lower drying rate at 30°C. This is consistent with SEM observations. With ageing the aggregates were more compact and less sensitive to drying.
The aggregated system indicated a higher initial drying rate (higher permeability), whereas stirring induced a lower drying rate, favouring the formation of compact laminar structure.
XRD peak intensity was lowered with ageing due to decrease in crystallinity (stacking faults and/or decrease in crystallite size). The content of amorphous material was lowered as well, reducing water sorption/desorption, which indicated that the specific surface is lower.
From the suitable microstructure induced by ageing some new phases may form (feldspar, zeolites), preferably in the coarser fraction of the sludge. This is disturbed by stirring which operation expels also carbonates from the particle edges and this may reduce the structural strength of the sludge. In aged bentonite suspension a similar tendency was observed of formation of specific microstructures capable of phase transformation, e.g. to feldspar.