The fate of acetochlor herbicide was investigated in corn /Zea mays L./ in nutrition solution culture experiments with and without R-25788 antidote. The antidote was found to slightly stimulate tthe absorption but retard the translocation of acetochlor labelled with14C in the carbonyl group. The degradation of the herbicide and the formation of the acetochlor GSH conjugate were faster in the antidote treated plants than in the untreated controls.
Fauna (last part), poisons and antidote, arms used by Indians for hunting and fishing
. This article is a transcript and French translation of the last four chapters (7 to 10) of Book 2 of the Latin manuscript by the Jesuit F. X. Eder on the missions or reductions in the Amerindian nations of the Moxos and Baures. It is the continuation of the first six articles on
the Jesuit missions in the now-Bolivian Amazon basin in the 18th century
Lima, Peru, and their inhabitants in the 18th century.
Jesuit missions in the now-Bolivian Amazon basin in the 18th century.
Quality of the soil and description of the Indians.
Constructive works, beliefs and superstitions of the Indians, and how to convince them to join a reduction.
Trees, fruits, plants and mammals.
Birds, hunting, crocodiles, dolphins, fishes and fishing.
Authors:Tamás Csermely, Georg Petroianu, Kamil Kuca, Józsel Fűrész, Ferenc Darvas, Zsolt Gulyás, Rudolf Laufer, and Huba Kalász
Quaternary pyridinium aldoximes have been analyzed by thin-layer chromatography. Their separation was adequate when silica plates were used with a mobile phase with a high water content. As a consequence of their limited migration, reversed-phase TLC was not appropriate for determination of the lipophilicity of quaternary pyridinium aldoximes. Displacement TLC of some quaternary pyridinium aldoximes is, nevertheless, possible using silica as stationary phase with water-acetone-hydrochloric acid mobile phases. Normal-phase TLC with different concentrations of organic modifier gave a series of
values for the pyridinium aldoximes. Approximation of the different plots of
against organic modifier concentration to straight lines afforded
values and the slopes of the lines. The
values and the slopes both serve as indicators of the hydrophilic character of the compounds.
Imazalil (IMA), a commonly used fungicide in both agricultural and clinical domains, is suspected to produce serious toxic effects in vertebrates. In recent years, a number of studies have suggested that lichens might be easily accessible sources of natural drugs that could be used as a possible food supplement. Extensive research is being performed to explore the importance of lichen species, which are known to contain a variety of pharmacological active compounds. In this context, the antigenotoxic effect of aqueous Dermatocarpon intestiniforme (Körber) Hasse. extract (DIE) was studied against the genotoxic damage induced by IMA on cultured human lymphocytes (n = 6) using chromosomal aberration (CA) and micronucleus (MN) as cytogenetic endpoints. Human peripheral lymphocytes were treated in vitro with varying concentrations of DIE (0, 25, 50 and 100 μg/ml), tested in combination with IMA (336 μg/ml). DIE alone were not genotoxic and when combined with IMA treatment, it reduced the frequency of CAs and the rate of MNs. A clear dose-dependent decrease in the genotoxic damage of IMA was observed, suggesting a genoprotective role of DIE. The results of the present study suggest that this plant extract per se does not have a genotoxic potential, but can alleviate the genotoxicity of IMA on cultured human lymphocytes. In conclusion our findings may have an important application for the protection of cultured human lymphocyte from the genetic damage and side effects induced by medical and agricultural chemicals hazardous for people.
Authors:Gellért Balázs Karvaly, Kornélia Tekes, Zoltán Szimrók, József FŰrÉsz, Kamil KuČa, and Huba Kalász
an efficient antidote would be imperative. Unfortunately, the effectiveness of current treatment protocols is unpredictable due to the weak effect of atropine on the central nervous system and the poor pharmacokinetic properties of the available
Authors:S. M. Nurulain, H. Kalász, P. Szegi, K. Kuca, A. Adem, M. Y. B. Hasan, F. Hashemi, and K. Tekes
HPLC monitoring of pharmacokinetics was done in two body compartments of rats following intramuscular treatments with three different doses of K027, a bispyridinium mono-aldoxime type of antidotes to organoposphate intoxicated subjects. Reversed-phase HPLC separation with electrochemical detections was done to monitor the onset, the maximum level, and offset in K027 concentration. Serum level of K027 showed a fast onset, independently from the doses of K027. Drug level in brain was showing an essentially delayed kinetics.