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Orvosi Hetilap
Authors: Lajos Driesz, Éva Barabás, Ildikó Bodócs, Zoltán Szántó, György Herr, Gábor Bencsik, László Pál, and József Borbola

., Quinlan, D. J., van Ryn, J., et al.: Idarucizumab the antidote for reversal of dabigatran. Circulation, 2015, 132 (25), 2412–2422. 13 Kiss, R. G.: Direct oral

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Abstract  

The fate of acetochlor herbicide was investigated in corn /Zea mays L./ in nutrition solution culture experiments with and without R-25788 antidote. The antidote was found to slightly stimulate tthe absorption but retard the translocation of acetochlor labelled with14C in the carbonyl group. The degradation of the herbicide and the formation of the acetochlor GSH conjugate were faster in the antidote treated plants than in the untreated controls.

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: Oxford University Press . Henaff , M. ( 2015 ): The Humanities, the Arts, and the Market . In: Brower , J. – van Tuinen , S. Giving and Taking: Antidotes to a Culture

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Fauna (last part), poisons and antidote, arms used by Indians for hunting and fishing . This article is a transcript and French translation of the last four chapters (7 to 10) of Book 2 of the Latin manuscript by the Jesuit F. X. Eder on the missions or reductions in the Amerindian nations of the Moxos and Baures. It is the continuation of the first six articles on the Jesuit missions in the now-Bolivian Amazon basin in the 18th century , entitled:

  1. 1. Lima, Peru, and their inhabitants in the 18th century.
  2. 2. Jesuit missions in the now-Bolivian Amazon basin in the 18th century.
  3. 3. Quality of the soil and description of the Indians.
  4. 4. Constructive works, beliefs and superstitions of the Indians, and how to convince them to join a reduction.
  5. 5. Trees, fruits, plants and mammals.
  6. 6. Birds, hunting, crocodiles, dolphins, fishes and fishing.

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JPC - Journal of Planar Chromatography - Modern TLC
Authors: Tamás Csermely, Georg Petroianu, Kamil Kuca, Józsel Fűrész, Ferenc Darvas, Zsolt Gulyás, Rudolf Laufer, and Huba Kalász

Quaternary pyridinium aldoximes have been analyzed by thin-layer chromatography. Their separation was adequate when silica plates were used with a mobile phase with a high water content. As a consequence of their limited migration, reversed-phase TLC was not appropriate for determination of the lipophilicity of quaternary pyridinium aldoximes. Displacement TLC of some quaternary pyridinium aldoximes is, nevertheless, possible using silica as stationary phase with water-acetone-hydrochloric acid mobile phases. Normal-phase TLC with different concentrations of organic modifier gave a series of R M values for the pyridinium aldoximes. Approximation of the different plots of R M against organic modifier concentration to straight lines afforded R M,0 values and the slopes of the lines. The R M,0 values and the slopes both serve as indicators of the hydrophilic character of the compounds.

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Imazalil (IMA), a commonly used fungicide in both agricultural and clinical domains, is suspected to produce serious toxic effects in vertebrates. In recent years, a number of studies have suggested that lichens might be easily accessible sources of natural drugs that could be used as a possible food supplement. Extensive research is being performed to explore the importance of lichen species, which are known to contain a variety of pharmacological active compounds. In this context, the antigenotoxic effect of aqueous Dermatocarpon intestiniforme (Körber) Hasse. extract (DIE) was studied against the genotoxic damage induced by IMA on cultured human lymphocytes (n = 6) using chromosomal aberration (CA) and micronucleus (MN) as cytogenetic endpoints. Human peripheral lymphocytes were treated in vitro with varying concentrations of DIE (0, 25, 50 and 100 μg/ml), tested in combination with IMA (336 μg/ml). DIE alone were not genotoxic and when combined with IMA treatment, it reduced the frequency of CAs and the rate of MNs. A clear dose-dependent decrease in the genotoxic damage of IMA was observed, suggesting a genoprotective role of DIE. The results of the present study suggest that this plant extract per se does not have a genotoxic potential, but can alleviate the genotoxicity of IMA on cultured human lymphocytes. In conclusion our findings may have an important application for the protection of cultured human lymphocyte from the genetic damage and side effects induced by medical and agricultural chemicals hazardous for people.

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341 Devlin, R. M., Zbiec, I. I. (1990): Effect of BAS-145-138 as an antidote for sulphonylurea herbicides. Weed Technol. , 4 , 337

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, antidotes of organophosphorous esterase inhibitors. Journal of Planar Chromatography 39–44 (2007) Kalasz H Journal of Planar Chromatography 2007 Eddleston M, Szinicz L

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] 22 Shihana F, Dawson AH, Dobbins T, et al. A bedside test for methaemoglobinemia improved antidote use in propanil poisoning. Clin Toxicol (Phila) 2016; 54: 576

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an efficient antidote would be imperative. Unfortunately, the effectiveness of current treatment protocols is unpredictable due to the weak effect of atropine on the central nervous system and the poor pharmacokinetic properties of the available

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