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Introduction Bone marrow is the largest hematopoietic organ in mammals. It compounds from 3% to 5% of total body weight [1] . Hematopoiesis in bones begins at the prenatal period and continues throughout life [2] . Therefore
, 2011. Nagasawa, T., Omatsu, Y., Sugiyama, T.: Control of hematopoietic stem cells by the bone marrow stromal niche: the role of reticular cells. Trends Immunol., 2011, 32 (7), 315
Salamon, A., Toldy, E.: The role of adult bone marrow derived mesenchymal stem cells, growth factors and carriers in the treatment of cartilage and bone defects. J. Stem Cells, 2009, 4 , 71–78. Toldy E
immunomodulatory effects of PQ to murine bone marrow-derived macrophages (BMDMs), which differ from the macrophage cell lines in the cytokine profiles, the phagocytic process and the ability to evoke oxidative burst ( Trouplin et al., 2013 ). Therefore, the aim of
engineering Arthr. Res. Ther. 5 532 – 544 . [3]. E. Jones D. McGonagle 2008 Human bone marrow mesenchymal stem cells in vivo Rheumatology 47 126 – 131 . [4]. W. Richter 2002 Stem cells and cartilage regeneration Akt
Repair of infarcted myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humans. Circulation, 2002, 106 , 1913–1918. Zeus T. Repair of infarcted
326 Kovalkovičová, N., Šutiaková, I., Legáth, J., Legáth, L’., Falis, M., Pistl, J., Kováč, G. (2004) Induction of micronuclei in rat bone marrow after subchronic inhalation exposure to
Matsumoto, T., Okamoto, R., Yajima, T. és mtsai: Increase of bone marrow-derived secretory lineage epithelial cells during regeneration in the human intestine. Gastroenterology, 2005, 128
Jones, E., McGonagle, D.: Human bone marrow mesenchymal stem cells in vivo. Rheumatology, 2008, 47 , 126–131. McGonagle D. Human bone marrow mesenchymal stem cells in vivo
Tateishi-Yuyama, E., Matsubara, H., Murohara, T. és mtsai: Therapeutic angiogenesis for patients with limb ischemia by autologous transplantation of bone marrow cells: a pilot study and a randomized controlled trial. Lancet, 2002, 360 , 427
