The incorporation of Se into some mice organs after injections of seleno-cystamine [(Se-Cta)2] in the presence of glutathione, cysteine, methionine, cysteamine, 6-mercaptopurine, 2-mercaptopurine and UO
has been studied. Variations in the Zn, Rb, Co, Fe and Hg contents were determined in all examined organs after intraperitoneal injections with the above compounds. Instrumental neutron activation analysis was applied as the analytical method. It was found that injected compounds affect the Se-distribution in the organs examined. Single applied intraperitoneal injection of (Se-Cta)2 or UO
lead to variations in the Zn, Rb, Co, Fe and Hg contents in mice organs.
Authors:A. Marchi, L. Uccelli, L. Magon, M. Bonardi, M. Gallorini, F. Groppi and S. Saponaro
The synthesis and scintigraphic studies in rats of99mTc-amino acid complexes containing the TcN multiple bond are reported. Chromatographic analysis shows the formation of a multicomponent system affected by tertiary phosphines employed as reducing agents of pertechnetate-99m in the systhesis of the complexes with cysteine (CYS) and cysteine ethyl ester (CYS-OEt), while no influence of them is observed in99mTc-complexes having cysteamine (CSA) as ligand. Electrophoresis stresses a strong anionic character in all these compounds. It has not been possible to define their chemical identity by a comparison with the neutral technetium-99 nitrido complexes characterized by spectroscopic and X-ray crystallographic data due to the complexity of the99mTc-system. These complexes are stable at 80 °C over a period of 2 hours. Time-activity curves indicate a renal tissue retention only for the99mTc-(CSA) complexes.
Authors:Saleh Alqasoumi, Mohammed Al-Dosari, Mohammed Al-Sohaibani, Tawfeq Al-Howiriny, Mohammed Al-Yahya and Syed Rafatullah
– 1231 .
. P. J. S. Chiu C. Gerhart A. D. Brown 1984 Effects of a gastric antisecretory cytoprotectant 2-methyl-8-(phenylmethoxy)imidazo (1,2-a)-pyridine-3-acetonitrile (Sch 28080) on cysteamine, reserpine and stress ulcers in rats
Özcan Arıcan, G. (2005) Cytoprotective effects of amifostine and cysteamine on cultured normal and tumor cells treated with paclitaxel in terms of mitotic index and 3H-thymidine labeling index.
Cancer Chemother. Pharmacol. 56
Authors:Caner Öztürk, Şükrü Güngör, Mehmet Bozkurt Ataman, Mustafa Numan Bucak, Nuri Başpinar, Pınar Ili and Muhammed Enes Inanç
Cirit , U. , Bagis , H. , Demir , K. , Agca , C. , Pabuccuoglu , S. , Varisli , O. , Clifford-Rathert , C. and Agca , Y. ( 2013 ): Comparison of cryoprotective effects of iodixanol, trehalose and cysteamine on ram semen . Anim. Reprod