the endocrine disruptors (EDs), which can influence the transmission of normal hormonal messages, simulating the real hormones or inhibiting their binding. Most of the EDs are human (industrial, agrotechnical, or communal) products; however, there are
Seneca, in the 114th piece of his Moral letters (written most
probably in the fall of 64 A.D.), evokes a part of Virgil's Georgics,
which he already quoted and construed more than 10 years earlier in De
clementia, addressed to Nero. At the same time, he lashes out on Maecenas.
Since Seneca mentions such characteristics of Maecenas that, according to
historical sources, resemble some of Nero's actions, and since he evokes a
fragment already analyzed for Nero, it seems very likely that the letter should
be viewed as the philosopher-statesman's critique of Nero.
Authors:Markus Krohn, Thomas Wanek, Marie-Claude Menet, Andreas Noack, Xavier Declèves, Oliver Langer, Wolfgang Löscher, and Jens Pahnke
successful humanization of the Abcg2 gene in mice by exchanging the 107 kbp mouse gene for the 141 kbp human gene. The approach may suffer from the unpredictability of disrupting long-range transcriptional elements or possible incompatibilities between
Our goal was to explore the interactions between the acoustic phenomena taking place in the ultrasound field, the concentration of the biological particles of the ultrasound field, and the cell biology effects of these interactions. Using output power of 9 W cm-2 and frequency of 1.117 MHz, the concentration was determined, expressed in g l-1, of lyophilized Saccharomyces cerevisiae baker's yeast needed for stopping cavitation in the sound field. Then by using multiples of the aforementioned concentration, we monitored the acoustic phenomena occurred in the sound field and, simultaneously, we examined the survival dynamics of the cells. Examined acoustic phenomena were the following: acoustic streaming, standing wave, and cavitation. Physical parameters (suspension density, dissolved oxygen, temperature) of the sound field had essential effect on the acoustic phenomena formed in the ultrasound field and on the threshold levels of their formation. The phenomena affected the composition of the material in the sound field, so an acoustical phenomenon - cell biological effect chain reaction took place during the radiation.