Authors:Hagen Frickmann, Andreas Hahn, Stefan Berlec, Johannes Ulrich, Moritz Jansson, Norbert Georg Schwarz, Philipp Warnke and Andreas Podbielski
systemic infections, both species can play a role in superficial infections such as wound infections [ 21 – 23 ] or in urinary tract infections [ 24 , 25 ].
While the etiologicalrelevance of both of these facultatively pathogenic species under the
Authors:Dorothea Wiemer, Norbert Georg Schwarz, Gerd-Dieter Burchard, Hagen Frickmann, Ulrike Loderstaedt and Ralf-Matthias Hagen
Diarrhoea is a frequent symptom associated with travelling to tropical regions, but the cause is often not found. Epidemiology was assessed including up-to-date real-time PCR approaches.
We analysed datasets of 528 patients who presented at the Bernhard Nocht Institute for Tropical Medicine in Hamburg, Germany, between 2006 and 2010 for screening purposes or because of diarrhoea. Stool samples were obtained and investigated by microscopy, bacterial culture, two PCR assays targeting Entamoeba histolytica, Entamoeba dispar, Giardia duodenalis, and Cryptosporidium parvum, or Salmonella spp., Shigella/EIEC spp., Campylobacter jejuni, and Yersinia spp.
Among patients with gastrointestinal symptoms, 51% tested positive for bacteria or parasites, of which 66% had a known enteropathogenic potential. In patients without diarrhoea, 53% (n = 80) were positive, and 33% of these cases harboured agents of pathogenic potential. Association with clinical symptoms was primarily found for bacterial infections. Blastocystis hominis, however, was more frequent in asymptomatic than in symptomatic travellers.
In conclusion, the study stresses the etiological relevance of bacterial gastroenteritis in travellers returning from the tropics, the need for molecular approaches to increase diagnostic sensitivity and demonstrates that asymptomatic carriage of enteropathogens after prolonged stays in the tropics is similarly frequent compared with symptomatic infections in travellers.
Authors:Hagen Frickmann, Thomas Köller, Ralf Matthias Hagen, Klaus-Peter Ebert, Martin Müller, Werner Wenzel, Renate Gatzer, Ulrich Schotte, Alfred Binder, Romy Skusa, Philipp Warnke, Andreas Podbielski, Christian Rückert and Bernd Kreikemeyer
Libyan patients' hospital stay at the Bundeswehr hospital Hamburg. With 29 out of 66 strains having potential etiologicalrelevance, colonizing bacteria dominated quantitatively.
From 24 isolates that were formally considered as nosocomially transmitted