Search Results

You are looking at 1 - 10 of 179 items for :

  • "guinea pig" x
  • All content x
Clear All

Gaschen, L., Ketz, C., Lang, J., Weber, U., Bacciarini, L. and Kohler, I. (1998): Ultrasonographic detection of adrenal gland tumor and ureterolithiasis in a guinea pig. Vet. Radiol. Ultrasound 39 , 43-46. Ultrasonographic

Restricted access
Acta Veterinaria Hungarica
Authors: Anna Linda Nógrádi, Iain Cope, Márton Balogh, and János Gál

. DeCubellis , J. and Graham , J. ( 2013 ): Gastrointestinal disease in guinea pigs and rabbits . Vet. Clin. North Am. Exot. Anim. Pract. 16 , 421 – 435 . Dudley , E. S. and Boivin

Restricted access
Acta Microbiologica et Immunologica Hungarica
Authors: Natalya V. Permyakova, Pavel A. Belavin, Dariya S. Pirozhkova, Elena G. Ufimtseva, Sergey M. Rozov, Sergey R. Mursalimov, Yuriy V. Sidorchuk, Elena A. Uvarova, Alla A. Zagorskaya, Tatiana V. Marenkova, Svetlana V. Bannikova, Evgeniy A. Demidov, Konstantin V. Starostin, Marionella A. Kravchenko, Diana V. Vakhrusheva, Roman B. Berdnikov, Natalya I. Eremeeva, Sergey N. Skornyakov, Sergey E. Peltek, and Elena V. Deineko

in a guinea pig TB model. The guinea pig TB model is widely used to assess the efficiency of new anti-TB vaccine candidates [ 13 ]. Unlike the model that utilizes mice, which are apt to develop a latent TB variant, the specific feature of the

Restricted access

Bolger GT, Gengo P, Klockowski R, Siegel H, Janis RA, Triggle AM, Triggle DJ: Characterization of binding of the Ca 2+ channel antagonist [ 3 H]nitrendipine to guinea-pig ileal smooth muscle. J. Pharmac. Exp

Restricted access
Acta Microbiologica et Immunologica Hungarica
Authors: Fatema Moni Chowdhury, Mohammed Ziaur Rahman, Md Murshed Hasan Sarkar, Fazle Rabbi, Sirajul Islam Khan, Chowdhury Rafiqul Ahsan, and Nils-Kåre Birkeland

vaccine in the guinea pig eye model against S. dysenteriae type 4 challenge. It also induced a high titer of serum IgG against S. dysenteriae type 4 whole cell lysate (WCL) and LPS. On the whole, DM104 could be a good choice as a live vaccine candidate

Restricted access

. (1996) Kappa-opioid receptor-like immunoreactivity in guinea-pig brain: ultrastructural localization in presynaptic terminals in hippocampal formation. J. Comp. Neurol. 370 , 377-395. Kappa-opioid receptor-like immunoreactivity

Restricted access

-induced contraction in rat and guinea-pig smooth muscles in vitro. Eur. J. Pharmacol. 281, 279-288 (1995) Multiple mechanisms of bradykinin-induced contraction in rat and guinea-pig smooth muscles in vitro Eur. J

Restricted access

In this study we conducted in-vitro incubation of whole-tissue homogenate of young adult guinea pig heart, kidney, testis, and spleen at pH 7.4 and 38°C for 60 min. Subsequent TLC analysis revealed:

  1. (a) a noticeably high level of MLCL and a very low level of CL in control testis, indicating possible in-vivo deacylation of CL
  2. (b) a high level of CL in control guinea pig heart and kidney samples, and no MLCL detected
  3. (c) MLCL was only produced (in both heart and kidney) subsequent to in-vitro incubation
  4. (d) a very low level of CL was present in control samples of guinea pig spleen and no MLCL was produced subsequent to in-vitro incubation
  5. (e) guinea pig heart contains both ethanolamine (PE) and choline plasmalogens (PC)
  6. (f) PE plasmalogen is the only alkenyl species present in guinea pig kidney, testes, and spleen
  7. (g) sphingomyelin (SM) is uniquely higher in kidney than testis and spleen and very low in the heart
  8. (h) subsequent to in-vitro incubation, ceramide is produced in the kidney and testes only, with concurrent reduction of SM, indicating endogenous action of sphingomyelinase on SM.
These data raised some questions pertaining to the lipolytic capabilities of diverse tissues and will be discussed in detail.

Restricted access

Bolser DC, Aziz SM, DeGennaro FC, Kreutner W, Egan RW, Siegel MI, Chapman RW: Antitussive effects of GABAB agonists in the cat and guinea-pig. Br. J. Pharmacol. 110(1), 491-495 (1993

Restricted access

For lack of relevant data of the literature, the tetanus immunisation results obtained in the two sexes were compared in an animal model. Complete immunisation series of weaned, adult and aged guinea-pigs (20–25 animals/group) were performed with aluminium phosphate (AlPO4) adsorbed purified tetanus toxoid (PTAP) as well as with typhoid-tetanus vaccine (TY-TE) containing lipopolysaccharide (LPS). Both vaccines contained 5.0 Lf (limes flocculans, Ramon) per single dose of tetanus toxoid, purity degree: 1500 Lf/mg protein nitrogen (PN). Tetanus antitoxin titres (TAT) were measured after the first shot, and subsequently before and after booster. Compared to TAT of male animals, significantly lower titres were found in female animals after basic immunisation with PTAP in all the three age groups: 1.03 vs. 0.57, 8.75 vs. 5.64, and 0.27 vs. 0.15 IU (international units, related to the Copenhagen International Standard) per ml (sex-chromosome-dependent differences?), as well as in adult animals immunised with TY-TE, before booster: 0.07 vs. 0.02 IU/ml (hormone-dependent differences?). In the latter case the TAT results after booster were 14.49 vs. 12.89 IU/ml. Thus, the lower female prebooster titres were counterbalanced by a quick and effective increase of titres following booster. These results are in accordance with our previous observations in humans (Réthy and Réthy, 1986). From our observations with tetanus immunisation series on guinea-pigs it can be concluded that TAT may be influenced by the effects of sex chromosomes as well as of sexual hormones. During active anti-tetanus immunisation with LPS-containing vaccine (TY-TE) the lower adult female prebooster titres are presumably counterbalanced by the better functionality of the female immune memory.

Restricted access