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Bipolaris sorokiniana (Sacc.) Shoemaker (Teleomorph: Cochliobolus sativus (Ito and Kuribayashi) Drechs. Ex. Dastur) is a serious necrotrophic pathogen of wheat and barley in several countries. In this paper we report on mechanism of resistance and histopathological changes that occur on pathogen attack in resistant and susceptible genotypes. Callose deposition was observed in the epidermal cell wall of resistant genotype, Pusa T3336 at 2DAI. Lignin deposition around mesophyll tissues was also strongly observed by Phloroglucinol-HCl test in Pusa T3336. Four days after inoculation (4DAI), the pathogen colonized the leaf tissues showing inter and intracellular hyphae in susceptible genotype, Agralocal. In resistant genotype, no colonization was observed. The host tissue in susceptible genotype showed degeneration away from the site of colonization and also showed loss of structural integrity thereby indicating the role of toxin in pathogenesis. Separation of plasmalemma from the cell wall was observed due to loss of electrolytes and degradation of chloroplast at 5 DAI in the susceptible genotypes was prominently seen through light microscopy.

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Acta Veterinaria Hungarica
Authors: Mohamed Abdelsalam, Mamdouh Y. Elgendy, Mohamed Shaalan, Mohamed Moustafa and Masayuki Fujino

. Chang , P. H. and Plumb , J. A. ( 1996 ): Histopathology of experimental Streptococcus sp.infection in tilapia, Oreochromis niloticus, and channel catfish, Ictalurus punctatus . J. Fish Dis. 19 , 235 – 241

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Twenty pullets and adult chickens, aged 100 to 403 days, from several commercial chicken farms were examined by gross and histopathology. Grossly, all chickens had white-greyish masses in the visceral organs with or without enlargement of the peripheral nerves. Histopathological examination revealed Marek’s disease (MD) lymphoma, lymphoid leukosis (LL) and myeloid leukosis (ML) in 14/20, 5/20 and 1/20 of the chickens, respectively. Lesions of the sciatic nerves in chickens diagnosed as having MD lymphoma were various. No neoplastic and/or inflammatory cells were noted in the peripheral nerves of chickens diagnosed as having LL and ML. These results indicated that MD lymphoma could also develop in older chickens; thus, microscopic examination is needed to identify MD in older chickens showing lymphocyte-derived tumours.

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Acta Veterinaria Hungarica
Authors: Elena Palade, Nóra Biró, Mihály Dobos-Kovács, Zoltán Demeter, Míra Mándoki and Miklós Rusvai

From a total of 1819 great tits ( Parus major ) ringed in 2007 in Pilis Mountains, Hungary, 15 birds presented nodular proliferative lesions on different areas of the head and eyelids, suggesting a poxvirus infection. Three birds were submitted for analysis. The presence of avipoxvirus infection was confirmed by histopathology, electron microscopy (EM) and a polymerase chain reaction (PCR) based technique. Nucleotide sequence analysis of a 428 base pairs (bp) fragment of the viral 4b core protein gene revealed 100% identity between two of the Hungarian isolates (PM9 HUN, PM33 HUN) and two great tit poxvirus strains isolated in Norway in 1973 (GTV A256, GTV A311). The third Hungarian isolate (PM34 HUN) was more closely related to a different Norwegian isolate (GTVA310) than to the Hungarian isolates. The nucleotide sequence analysis of a shorter fragment of the viral 4b core protein (227 bp) gene revealed 100% identity between the Hungarian isolates, the same Norwegian isolates and a great tit poxvirus strain detected in Austria in 2007.

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Dropkin, V. B. and Nelson, P. E. (1960): The histopathology of RKN infections in soybean. Phytopathology 50, 442–447. Nelson P. E. The histopathology of RKN infections in soybean

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was observed in hepatocytes Discussion In this study, we evaluated the effect of swimming training on oxidative stress, SIRT1 gene expression, and histopathology of hepatic tissue in

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One of the most serious problems in the chinchilla industry is 'fur-chewing', when the chinchilla bites off areas of its own or some other animal's fur. The condition generally develops in both genders at the age of 6-8 months. In chinchilla farms in Croatia an incidence of 15-20% has been observed. A pathomorphological, microbiological and parasitological investigation was conducted on eleven 6- to 11-month-old chinchillas of both sexes with clinical symptoms of 'fur-chewing' and three chinchillas without such signs. Histopathology of the adrenal glands and of the chewed skin revealed changes typical of Cushing's syndrome in 'fur-chewed' chinchillas, such as hyperkeratinisation of the epidermis, epidermal atrophy, pronounced follicular and sebaceous gland atrophy, hyperkeratinisation of the follicles with comedo formations and the presence of calcium salts in subcutis.

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Orvosi Hetilap
Authors: Bernadett Fakan, Eszter Baranyi, Réka Horváth, Endre Kálmán, Janina Kulka, Katalin Tölgyesi, Miklós Török, Nóra Udvarhelyi, Tamás Zombori and Gábor Cserni

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Bevezetés: Szervmegtartó műtéttel eltávolított emlőrákoknál fontos a sebészi szélek állapotának vizsgálata, dokumentálása. Ha az eltávolítás nem az épben történik, általában kiegészítő kezelés (ismételt sebészet, tumorágy-besugárzás) javasolt. Célkitűzés: Szervmegtartó műtéttel eltávolított női emlőrákok patológiai leleteinek sebészi szélekre vonatkozó információtartalmának elemzése, a nem ép szélek gyakoriságának felmérése és nem ép szélek esetén a további kezelések gyakoriságának becslése. Módszer: Nyolc magyar patológiai részlegből származó, mellrák miatt végzett szervmegtartó műtéthez tartozó patológiai leletek elemzése, nem ép szél esetén további lokális kezelésre vonatkozó adatok gyűjtésével. Eredmények: Kizárások után 386 leletet elemeztünk. Az ép szél korábbi definíciója (<5 mm) alapján 200, az újabb értelmezés (0 mm) alapján 32 lelet dokumentált nem ép széleket. Lobularis carcinoma esetén gyakoribb volt a szélek pozitivitása, mint nem lobularis rákok esetén. Az épben eltávolított tumorok műtéti anyaga nagyobb tömegű volt. Reoperáció 43/180, illetve 12/22 esetben történt a régi és az új definíció szerinti nem ép szélek esetén. A nem reoperált betegek közül csak 75/137 kapott biztosan külön tumorágy-besugárzást; sok esetben a ’boost’ kezelésről nem állt rendelkezésre információ. Reziduális tumor a reoperált betegek közül csak 15/43-nál igazolódott, 9-nél közülük úgy, hogy a festett szélben a primer műtéti anyagban nem írtak le daganatot. Következtetések: A patológiai leletek sebészi szélre vonatkozó információtartalma nem teljes körű. Az új biztonságos szél definíciója csökkentette a nem ép szél előfordulási gyakoriságát, de alkalmazásakor ép szélek mellett is maradhat reziduális daganat az emlőben, amint azt a reoperációs minták igazolják. Nem épben történő tumoreltávolításkor az esetek egy részében nem történik sem további sebészi kezelés, sem külön tumorágy-besugárzás. Orv Hetil. 2019; 160(26): 1036–1044.

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Orvosi Hetilap
Authors: Balázs Liktor, Andor Hirschberg, Bálint ifj Liktor and Tamás Karosi

Karosi T, Csomor P, Petkó M, et al. Histopathology of nonotosclerotic stapes fixations. Otol Neurotol. 2009; 30: 1058–1066.

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The presence of Yersinia ruckeri, the causal agent of enteric redmouth dis- ease (ERM) in salmonids and a few other freshwater fish, has so far been reported from a variety of sources including the intestine of healthy carp. Since there are no data on the pathogenicity of this bacterium for carp, 15 fingerlings were experi- mentally infected by intraperitoneal injection of about 5 × 105 cells. Thirteen in- jected fish were moribund or died within 4 days with septicaemic lesions. Two survivors were sampled on Day 28 after infection. Yersinia ruckeri was reisolated from the internal organs of all experimental fish. By histopathological examination moribund fish had generalised bacteriaemia with inflammation, degeneration and necrotic foci in kidney, liver and spleen, corresponding to findings described pre- viously in ERM of rainbow trout. Survivors of challenge on Day 28 had a chronic disease characterised by prominent peritonitis and enteritis, exhaustion of the erythroid, granuloid and lymphoid components in haematopoietic kidney tissue as well as focal degeneration and necrosis in organs. These data indicate a high sen- sitivity of carp to intraperitoneal infection with a relatively low dose of Y. ruckeri.

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