Authors:Murat Gözüküçük, Aslı Yarcı Gürsoy, Duygu Kankaya, and Cem Atabekoglu
the uterine cervix with PAN-like lesions, in the presence of cervical intraepithelial neoplasia grade III (CIN 3) and accompanying humanpapillomavirus (HPV) infection, in view of the previous literature.
deVilliers, E., M., Wagner, D., Schneider, A., Wesch, H., Miklaw, H., Wahrendorf, J., Papendick, U., Zur Hausen, H.: Humanpapillomavirus infection in women without and with abnormal cervical cytology. Lancet, i
A history of having
exposure as detected by serum
antibodies is a cofactor of human papillomavirus (HPV) mediated cervical
carcinogenesis. In this study, we examined the concurrent
infections in cytologic atypia of the uterine cervix in order to evaluate the
infection in patients with high risk for
cervical intraepithelial neoplasia. Cervical scrapes form 707 patients were
subjected to PCR amplification with primer sets for HPV and
Based on negative beta-globin results, 10 specimens were not eligible for
further analysis. Oncogenic HPV types were detected in 278 specimens (39.8%).
was found only in six specimens (0.9%). In conclusion,
infection was uncommon and hence it was an
improbable risk factor in cytologic atypia.