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. (ed.): Professional and organizational guidelines of treatment of hypertension in adults and children. [A hypertoniabetegség felnőttkori és gyermekkori kezelésének szakmai és szervezeti irányelvei.] Hypertonia és Nephrologia, 2009, 13 (Suppl. 2) , 89
World Heart Federation: Cardiovascular Disease Risk Factor: Hypertension. http://www.world-heart-federation.org/cardiovascular-health/cardiovascular-disease-risk-factors/hypertension
Henderson, A. D., Bruce, B. B., Newman, N. J., et al.: Hypertension-related eye abnormalities and the risk of stroke. Rev. Neurol. Dis., 2011, 8 , 1
hypertension. The task force of the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). J. Hypertens., 2007, 25 , 1105–1187. Dominiczak
It is now well accepted that alterations in kidney function, due either to primary renal disease or to inappropriate hormonal influences on the kidney, are a cardinal characteristic in all forms of hypertension, and lead to a reduced ability of the kidneys to excrete sodium and the consequent development of elevated arterial pressures (1, 2). However, it is also apparent that many extrarenal factors are important contributors to altered kidney function and hypertension. Central to many hypertensinogenic processes is the inappropriate activation of the renin-angiotensin system (RAS) and its downstream consequences by various pathophysiologic mechanisms (3, 4). There may also be derangements in arachidonic acid metabolites, endothelium derived factors such as nitric oxide and carbon monoxide, and various paracrine and neural systems that normally interact with or provide a counteracting balance to the actions of the RAS. Thus, when the capacity of the kidneys to maintain sodium balance and extracellular fluid volume within appropriate ranges is compromised, increases in arterial pressure become necessary to re-establish normal balance (2, 5, 6).
Introduction Hypertension is the largest global epidemic disease that threatens health in advanced countries [ 1 ]. Blood pressure is the amount of force exerted upon the arterial wall to allow blood flow throughout the body
cardiovascular mortality. Curr. Atheroscler. Rep., 2002, 4 (2), 120–127. Mussalo, H., Vanninen, E., Ikäheimo, R., et al.: Heart rate variability and its determinants in patients with severe or mild essential hypertension
Mancia, G., Fagard, R., Narkiewicz, K., et al.: 2013 ESH/ESC guidelines for the management of arterial hypertension: the Task Force for the Management of Arterial Hypertension of the European Society of
patients with NASH have progression of liver fibrosis [ 2 , 3 ]. Considerable attention is paid to the close relationship between NAFLD and cardiovascular diseases (CVD), especially to comorbidity with arterial hypertension (HT) that affects about 30% of
transfer of the client peptides across membranes. HSP70 has been implicated in the pathogenesis of atherosclerosis and as an autoantigen in the pathogenesis of hypertension. – HSP90. HSP90 is a member of the HSPC family. It has an ATP-binding amino