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such a treatment is the use of ibogaine as an opioid detoxification treatment. Ibogaine history and evidence for use as a treatment for opioid addiction Ibogaine is a naturally occurring alkaloid, obtained from the root bark

Open access
Journal of Psychedelic Studies
Authors:
Clare Wilkins
,
Rafael G. dos Santos
,
Jordi Solá
,
Marc Aixalá
,
Pep Cura
,
Estefanía Moreno
,
Miguel Ángel Alcázar-Córcoles
,
Jaime E. C. Hallak
, and
José Carlos Bouso

terminated MMT ( Pedrero-Pérez & MethaQoL, 2016 ). It is clear that novel pharmacological treatments that are effective in ceasing opioid misuse are necessary. Ibogaine is the principal alkaloid in Tabernanthe iboga , an African plant used in

Open access

Introduction Ibogaine is a naturally occurring indole alkaloid derived from the root barks of Tabernanthe iboga , a plant native to western Central African countries such as Gabon and Cameroon, where it has been used

Open access
Journal of Psychedelic Studies
Authors:
Thaddeus James Camlin
,
Donald Eulert
,
Arthur Thomas Horvath
,
Steven F. Bucky
,
Joseph P. Barsuglia
, and
Martin Polanco

Introduction Ibogaine is a naturally occurring indole alkaloid derived from the roots of Tabernanthe iboga , a bush common in the equatorial under forests of Western Africa ( Stafford, 1993 ). Sparked by anecdotal testimonials

Open access
Journal of Psychedelic Studies
Authors:
Eduardo Ekman Schenberg
,
Maria Angélica de Castro Comis
,
João Felipe Morel Alexandre
,
Luís Fernando Tófoli
,
Bruno Daniel Rasmussen Chaves
, and
Dartiu Xavier da Silveira

Introduction Ibogaine is a naturally occurring monoterpene indole alkaloid studied since the 1960s as having important therapeutic properties in the treatment of drug dependence, specially reducing cravings to opioids ( Alper

Open access

. Unfortunately, many individuals have to be on OAT for prolonged periods of time, or for whom this therapy is not effective, leaving few other treatment options. Ibogaine offers an alternative or adjunct treatment for OUD, with potential for rapid titrations off

Open access
Journal of Psychedelic Studies
Authors:
Eduardo Ekman Schenberg
,
Maria Angélica de Castro Comis
,
João Felipe Morel Alexandre
,
Bruno Daniel Rasmussen Chaves
,
Luís Fernando Tófoli
, and
Dartiu Xavier da Silveira

& Kosten, 2011 ). One possible route in the development of a new therapeutic approach for drug abuse and dependence is the use of ibogaine, an alkaloid extracted from the root bark of Tabernanthe iboga ( Alper, 2001 ; Alper, Beal, & Kaplan, 2001 ; Brown

Open access

opioids such as fentanyl in illicit drug markets. Against the background of the current scientific renaissance in psychedelics and using previously prohibited psychoactive substances as therapeutic agents ( Bright, Williams, & Caldicott, 2017 ), ibogaine

Open access

research exploring novel pharmacologic drugs for this vulnerable population. Therefore, the primary aim of this observational study is to assess whether psychedelic treatment with ibogaine and 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is associated with

Open access

psychedelic substances for the treatment of psychological disorders. This has included the administration of a range of substances, including LSD, psilocybin, ayahuasca, methylenedioxymethamphetamine (MDMA), and ibogaine, in conjunction with psychotherapy for

Open access