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marker of OTS, particularly in resistance training [ 13 ]. Irisin is a novel myokine and adipokine that has been found to increase adipocyte browning in subcutaneous fat, as well as promoting thermogenesis regulated by uncoupling protein 1 (UCP1) and

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energy intake and consumption due to the release of hormones from muscles and adipose tissues ( 22 ). Irisin is a myokine hormone (112 amino acids) that was discovered in 2012 ( 43 ). This hormone is produced by the proteolytic breakdown of the

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these adipokines, such as irisin, chemerin, and asprosin has been reported to participate in pathological conditions (e.g., insulin resistance) and chronic inflammation [ 4–6 ]. Irisin has also been identified as a myokine derived from its

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irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise. Metabolism, 2012, 61 (12), 1725

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, Singapore, 2018; pp. 161–170. 25 Dozio E, Passeri E, Cardani R, et al. Circulating irisin is reduced in male patients with type 1 and type 2 myotonic dystrophies. Front Endocrinol

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Az artériás érfali merevség és a rendszeres testmozgás kapcsolata

Relationship between arterial stiffness and regular physical activity

Orvosi Hetilap
Authors: Ágnes Diószegi, Beáta Kovács, Szabolcs Lengyel, Sándor Szántó, Erika Kocsis, Dénes Páll, and Mariann Harangi

Inoue K, Fujie S, Hasegawa N, et al. Aerobic exercise training-induced irisin secretion is associated with the reduction of arterial stiffness via nitric oxide production in adults with obesity

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Physiology International
Authors: A Zlibut, IC Bocsan, RM Pop, SC Vesa, K Bheecarry, R Revnic, B Cojan-Minzat, S Lupu, AD Buzoianu, and L Agoston-Coldea

circulating irisin, retinol binding protein-4, adiponectin and inflammatory mediators in patients with metabolic syndrome . Arch. Endocrinol. Metab. 61 , 515 – 523 ( 2017 ) 10.1590/2359-3997000000289 25

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, Jiang M , Irisin promotes human umbilical vein endothelial cell proliferation through the ERK signaling pathway and partly suppresses high glucose-induced apoptosis . PloS

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