various forms of ketosis. Acta Vet. Beograd 56 , 25-36.
Adrenocortical and thyroid function, hor-mone and metabolite profiles and the onset of ovarian cyclicity in dairy cows suffering from various forms of ketosis
The energy imbalance related predisposition to mastitis was studied in group-fed postpartum dairy cows (n = 333) kept in 4 large-scale units and producing milk of low somatic cell count (SCC). Blood samples were taken on Days 1-3 after calving for assaying some metabolites and hormones related to the negative energy balance (NEB). If mastitis was diagnosed later, aseptic milk samples were taken to identify the pathogens. Considering pathogen types [contagious pathogens: Staphylococcus (S.) aureus, Gram-positive (GP) environmental pathogens, and Gram-negative (GN) environmental pathogens + mastitis with no detectable pathogens (NDP)] separately, stepwise logistic regression was used to analyse the relation between the potential prognostic value of hormones and metabolites and mastitis outbreak. Only the elevated (= 1.00 mmol/l) serum ß-hydroxybutyrate (BHB) levels predisposed the cows to mastitis in the subsequent 4 weeks. This prognostic value of BHB was significant only in GN + NDP mastitis and in cases caused by GP environmental pathogens, but not in S. aureus mastitis (odds ratio: 5.333, 3.600 and 1.333, respectively).
period is the time when metabolic and infectious disorders occur most frequently ( Ingvartsen, 2006 ), and clinical and subclinical ketosis, fatty liver, abomasal displacement, placental retention, metritis, and mastitis are reported to be the most common
An automatic flow injection (FIA) and two possible reference gas chromatographic (liquid and headspace sampling GC) methods including appropriate sample preparation were developed and validated for determination of acetone in milk. The methods were tested by preserved raw milk samples. The FIA results were compared with data obtained by GC determinations. It was found that FIA procedure is suitable for rapid automated measurement of acetone in the range of 0-5 mmol l-1 in milk, therefore it is a promising analytical method for ketosis monitoring in dairy farms.
] monitored the effects of KD on neuronal energy metabolism. The authors addressed whether the induction of peripheral ketosis could resolve the lack of circulating nutrients due to adipose tissue depletion in EAE mice. The study revealed a mitigation of
oxidation capacity and contributes to liver associated diseases like ketosis or fatty liver disease ( Ringseis et al., 2014 ). Disturbed ruminal function around the time of calving is nowadays considered normal ( Pahl et al., 2014 ; Kovács et al., 2017
reduce the incidence of ketosis ( Santschi et al., 2011 ). Cows in negative energy balance (NEB) with a prolonged interval to first ovulation have increased circulating levels of non-esterified fatty acids (NEFA) and reduced levels of insulin-like growth
) , 94 , 605 – 614 . 19906132 McArt , J. A. A. , Nydam , D. V. , Ospina , P. A. and Oetzel , G. R. ( 2011 ): A field trial on the effect of propylene glycol on milk yield and resolution of ketosis in fresh cows diagnosed with subclinical