Plant TM. Neuroendocrine control of the onset of puberty. Front Neuroendocrinol. 2015; 38: 73–88. 9 Cheng G, Coolen LM, Padmanabhan V, et al. The kisspeptin/neurokinin B
are suitable test subjects for newly discovered pharmacological agents ( 9 ). Studies over the past decade have revealed the regulatory role of kisspeptin in glucose homeostasis. A recent study in mice showed that KP-10 plays a direct role in
associated with decreased GnRH activation and kisspeptin fiber density in the hypothalamus. Neurotoxicology, 2008, 29 , 988–997. Patisaul H. B. Disrupted female reproductive physiology
the timing of puberty, development of the hypothalamic kisspeptin system . Endocrinology 152, 3396 – 3408 ( 2011 ) 10.1210/en.2010-1415 7. Chen H , Simar D , Lambert K , Mercier J , Morris MJ : Maternal, postnatal overnutrition