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& Hollmann, 2008 ; Pérez-Otaño, Larsen, & Wesseling, 2016 ). It has been reported that the expression of NMDA receptors is not limited to the neural cells; other cell types, such as lymphocytes, may also express NMDA receptors ( Boldyrev et al., 2004
Radiation damage to lymphocyte membranes
II. Structural changes of lipid domain after low doses of high let irradiation
Abstract
The changdes of some physical parameters of lymphocyte membranes following neutron irradiation from a252Cf sourcein vitro in range of very low doses were studied. We aimed our attention at fluorescence intensity, fluorescence polarisation, microviscosity and order parameter of lipid bilayer of lymphocyte membranes. The values of above mentioned parameters were obtained by means of fluorescent spectrometry using 1,6-diphenyl-1,3,5-hexatriene (DPH) as a fluorescent probe. It was shown, that with increasing doses of radiation the values of all studied parameters have been decreasing. The microviscosity of membranes decreased to 37% of the control value.
. Sokol, L., Luoghran, T. P. Jr.: Large granular lymphocyte leukemia. Oncologist, 2006, 11 (3), 263–273. Wlodarsky, M. W., O’Keefe, C., Howe, E. C., et al.: Pathologic clonal cytotoxic T-cell responses: nonrandom
ginsenosides on the growth of mice splenic lymphocytes have not been reported. Splenic lymphocytes are the important cells of immunologic system and play a significant role in host acute or chronic diseases. As the first step for T cell activation
Yoshimura, T., Kurita, C., Yamazaki, F. és mtsai: Lymphocyte stimulation test with tetrazolium-based colorimetric assay for diagnosis of drug-induced allergic hepatitis. Biol. Pharm. Bull., 1994, 17 , 921
. 59 31 681 Evans, H. J., O'Riordan, M. L. (1975) Human peripheral blood lymphocytes for the analysis of chromosome aberrations in mutagen tests
dichlorvos on cultured human lymphocytes. Arch. Toxicol. 30 , 75–85. Dean B. J. The effect of dichlorvos on cultured human lymphocytes Arch. Toxicol
Celik, M., Unal, F., Yüzbasioglu, D., Ergün, M. A., Arslan, O., Kasap, R. (2005) In vitro effect of karathane LC (dinocap) on humane lymphocytes. Mutagenesis 20 , 101–104. Kasap R. In
pharmacological properties [ 4 ]. For example, Rg 1 played dominant role in angiogenesis while Rb 1 showed inhibited effect in the earliest step of angiogenesis [ 5 ]. However, the effects of ginsenosides Rg 1 and Rb 1 on the growth of mice splenic lymphocytes
lymphocytes has not been studied from then on. Splenic lymphocytes are the important cells of immunologic system and play a significant role in a host of acute or chronic diseases. Within the cell growth, the various metabolic events are all heat
