References 1 Skin cancer – melanoma. American Cancer Society. http://www.cancer.org/cancer/skincancer-melanoma 2 Balch, C. M., Soong
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Introduction In equines, tumours of the skin and soft tissues account for 80% of all neoplasms and the three most frequent of them are sarcoids, squamous cell carcinoma and melanoma, the last mentioned having great importance because of its high
Leiter, U., Garbe, C.: Epidemiology of melanoma and nonmelanoma skin cancer – the role of sunlight. Adv. Exp. Med. Biol., 2008, 624 , 89–103. Garbe C
. M.E. Laing F.J. Moloney E.W. Kay 2006 Malignant melanoma in transplant recipients
Mda-7 or IL-24, a novel member of the IL-10 cytokine family has growth inhibitory effect on several human cancers including melanoma via selective apoptosis. Expression of IL-24 could be induced in human PBMC by treatment with phytohaemagglutinin, lypopolisaccharide, IL-4 or influenza A virus infection. Materials and Methods: Human PBMC were stimulated with staphylococcal strains originating from clinical specimens, and the appearance of IL-24 at the level of transcription and translation was followed by RT-nested PCR and Western blot assays. Results: All staphylococcal strains induced IL-24 mRNA. Staphylococci, pathogenic or not, did induce the production of IL-24 in PBMC, but there was a difference between the different staphylococcal strains in their effect on the production of the IL-24 protein. Conclusions: The pathogenic S. aureus or bacteria belonging to the normal flora of the skin ( S. epidermidis and S. saprophyticus ) as factors stimulating the production of the Mda-7 protein may be a crucial lead in the investigation of different skin lesions.
melanoma and other metastatic and primary skin tumors. Expert. Rev. Anticancer Ther., 2006, 6 , 671–678. Thompson J. F. Role of electrochemotherapy in the treatment of metastatic
F Marchetti MD Hellinger 2004 Primary malignant melanoma of the right colon Am Surg 70