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Journal of Flow Chemistry
Authors: Gary Perkins, Omar Khatib, Matthew Peterson, Annukka Kallinen, Tien Pham, Alison Ung, Ivan Greguric and Giancarlo Pascali

Carbon dioxide chemistry is an area of continuing growth in recent times, due to socioeconomic and environmental reasons. Several methods have now been reported for obtaining N-methylation on primary and secondary amines directly from CO2. We have translated in two microfluidic setups (Slug Flow [SF] and Tube-in-Tube [TiT]) a ruthenium (Ru)-catalyzed process previously reported using a pressure vessel. Here, we demonstrate how the SF approach is more efficient but requires more input to reach a steady state, while the TiT system is less efficient but more tuneable.We have tested these processes on three model amines and two radiopharmaceutical precursors that are routinely used in 11C chemistry. The microfluidic processes tested are also potentially more efficient than the pressure vessel counterpart, in terms of amount of Ru catalyst needed (1% vs. 10%) and projected reaction completion time.

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Ashikawa I (2001) Surveying CpG methylation at 5′-CCGG in the genomes of rice cultivars. Plant Molecular Biology 45 : 31–39 Ashikawa I

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Arnholdt-Schmitt, B., Herterich, S., Neumann, K. H. (1995) Physiological aspects of genome variability in tissue culture. I. Growth phase-dependent differential DNA methylation of the carrot genome ( Daucus

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Biologia Futura
Authors: Muhammad Saad, Helen Mary, Umar Amjid, Ghulam Shabir, Kashif Aslam, Shahid Masood Shah and Abdul Rehman Khan

process. Different epigenetic marks like DNA methylation and histone modification play their role in modulating the plant stress response. Among these, DNA methylation is most stable epigenetic mechanism that can have implications in crop

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Orvosi Hetilap
Authors: Sándor Spisák, Alexandra Kalmár, Orsolya Galamb, Ferenc Sipos, Barnabás Wichmann, Béla Molnár and Zsolt Tulassay

methylation in the regulation of transcription. Curr. Opin. Genet. Dev., 1994, 4 , 255–259. Cedar H. Role of DNA methylation in the regulation of transcription

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Orvosi Hetilap
Authors: Kinga Tóth, Orsolya Galamb, Sándor Spisák, Barnabás Wichmann, Ferenc Sipos, Katalin Leiszter, Jeannette Molnár, Béla Molnár and Zsolt Tulassay

63 2179 2187 Ebert, M. P., Model, F., Mooney, S. és mtsai: Aristaless-like homeobox-4 gene methylation is a potential marker for

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Abstract

This paper describes the next stage in our development of self-optimising reactors. We demonstrate that the same reaction can be optimised for a series of different criteria including yield, space–time yield, E factor and a weighted yield function (the product of space–time yield and yield). In different experiments, we achieved 97.6% yield, space–time yield of 42.9 kg/L/h and E factors of 1.4 and 3.3 (including CO2) and the weighted yield, which gave a promising balance between yield, E factor and space–time yield.

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Orvosi Hetilap
Authors: Krisztina Andrea Szigeti, Orsolya Galamb, Alexandra Kalmár, Barbara Kinga Barták, Zsófia Brigitta Nagy, Eszter Márkus, Péter Igaz, Zsolt Tulassay and Béla Molnár

methyltransferases. Front Genet. 2016; 7: 99. 3 Marinus MG, Casadesus J. Roles of DNA adenine methylation in host-pathogen interactions: mismatch repair, transcriptional regulation, and

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Pukkila, P. J.: Telling right from wrong: a role for DNA methylation. Trends in Genetics 3 , 1–2 (1987). Pukkila P. J. Telling right from wrong: a role for DNA methylation

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Orvosi Hetilap
Authors: Orsolya Dóra Ács, Bálint Péterfia, Péter Hollósi, Irén Haltrich, Ágnes Sallai, Andrea Luczay, Karin Buiting, Bernhard Horsthemke, Dóra Török, András Szabó and György Fekete

–12. 12 Wang W, Law HY, Chong SS. Detection and discrimination between deletional and non-deletional Prader–Willi and Angelman syndromes by methylation-specific PCR and quantitative melting curve analysis

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