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Orvosi Hetilap
Authors: Judit Bedekovics, László Rejtő, Béla Telek, Miklós Udvardy, Anikó Újfalusi, Éva Oláh, Zsuzsa Hevessy, János Kappelmayer, Béla Kajtár, and Gábor Méhes

Falini, B., Bolli, N., Shan, J. és mtsai: Both carboxy terminus NES and mutated tryptophans are crucial for aberrant nuclear export of nucleophosmin leukemic mutants in NPMc+ AML. Blood, 2006, 107 , 4514

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The article aims to assess the effectiveness of the non-proliferation regime established more than 40 years ago with the adoption of the Treaty on the Non-proliferation of Nuclear Weapons (NPT). Since that time the international community had achieved considerable success in the prevention of nuclear weapons’ proliferation. Nevertheless, while noting the results of the NPT and the verification system established under that instrument, one cannot remain silent about the shortcomings of the system and the non-compliance with some of its provisions. By its structure and provisions the NPT has divided States into two groups, distinguishing those possessing and those not possessing nuclear weapons. In effect, the rights and obligations of the Contracting Parties to the NPT are tailored to the group to which they belong, and the gravest violation of the NPT is that when States seek to change their status as defined in the NPT, notably by trying to munfacture or control of nuclear weapons. Under the NPT, research in, production and application of nuclear energy for peaceful purposes are inalienable rights, but their exercise should be in keeping with the basic obligation of nonnuclear-weapon States under the Treaty not to acquire in any form nuclear weapons and not to carry out unauthorized nuclear activities under the guise of their peaceful nuclear programs. While emphasizing the need to strengthen the non-proliferation regime, the article describes in nutshell the nuclear program of two States (the Islamic Republic of Iran and the Democratic People’s Republic of Korea) which gave cause for serious international concern.

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: requirement for the nuclear export factor Crm1 (Exportin) and the stress-activated MAP kinase Sty1/Spc1. Genes Dev. 12 , 1453–1463. Jones N. Regulation of the fission yeast transcription

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2012; 10: 239–245. 5 Yi R, Qin Y, Macara IG, et al. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev. 2003; 17: 3011

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. 2004 23 4051 4060 Lund E, Guttinger S, Calado A, Dahlberg JE, Kutay U: Nuclear export of microRNA precursors. Science

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Nuclear targeting of adenovirus type 2 requires CRM1-mediated nuclear export Mol Biol Cell 16 2999 – 3009 . 58. J

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Acta Veterinaria Hungarica
Authors: Thiago Henrique M. Vargas, Camila N. Barra, Lidia H. Pulz, Greice C. Huete, Karine G. Cadrobbi, Adriana Tomoko Nishiya, Silvia Regina Kleeb, José Guilherme Xavier, José Luiz Catão-Dias, and Ricardo F. Strefezzi

, T. , Oka , N. , Inohara , H. , Kim , H. R. , Bresalier , R. S. and Raz , A. ( 2004 ): Nuclear export of phosphorylated galectin-3 regulates its antiapoptotic activity in response to chemotherapeutic drugs . Mol. Cell Biol. 24 , 4395

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