Search Results

You are looking at 1 - 3 of 3 items for :

  • "perfluoroalkylation" x
  • Refine by Access: All Content x
Clear All
Journal of Flow Chemistry
Authors: Natan Straathof, Dannie Osch, Arian Schouten, Xiao Wang, Jaap Schouten, Volker Hessel, and Timothy Noël

A visible light photocatalytic metal-free perfluoroalkylation method for the functionalization of heteroarenes in continuous flow was developed. Eosin Y was the most efficient photocatalyst with regard to substrate scope, reaction time and cost prize. Faster reaction times were observed in continuous flow compared to batch due to an improved irradiation of the reaction mixture on a microscale. Several pyrroles and indoles were perfluoroalkylated within 30 min residence time (six examples). The trifluoromethylation of pyrroles and indoles was achieved by using a gas–liquid flow with CF3I as a cheap CF3 source (three examples).

Restricted access

– 1185 . “ Rapid trifluoromethylation and perfluoroalkylation of five-membered heterocycles by photoredox catalysis in continuous flow ” N. J. W. Straathof , H. P. L. Gemoets , X. Wang , J. C. Schouten , V. Hessel , T. Noël

Restricted access

PET radioligands through the radiofluorination of diaryliodonium tosylates ” S. Telu , J.-H. Chun , F. G. Simeon , S. Lu , V. W. Pike Organic & Biomolecular Chemistry 2011 , 9 , 6629 – 6638 . “ Perfluoroalkylation in

Restricted access