between intra-uterine bacterial contamination, endotoxin levels and the development of endometritis in postpartum cows with dystocia or retained placenta. Theriogenology 54 , 1019–1032.
Lohuis J. A. C. M
External beam PIXE analysis with a protonbeam of 2.4 MeV was used to study trace element concentrations in human placentas. The aim was to check the suitability of PIXE analysis regarding soft tissue samples. Sample preparation was kept as simple as possible to avoid contamination or losses due to volatilization. The element of interest /Fe, Cu, Zn, Se, Br, Rb, and Sr/ were easily detected. A comparison was made with placental samples of alcoholics and abstinent controls to determine whether trace element concentrations in the placenta play a role in the pathogenesis of fetal alcohol syndrome.
The concentrations of extractable organohalogens (EOX) and extractable persistent organohalogens (EPOX) in placenta, umbilical
cord and hair of mothers delivering disabled or normal newborns as well as the compositions of EPOCl in three analyzed matrices
were determined by a combination of NAA, gas chromatography and chemical separation. The results indicated that both EOX and
EPOX decreased in the order: hair > umbilical cord > placenta. Organochlorines were the major fraction of organohalogens.
More than 77% of EPOCl were unidentified. High organohalogens exposure may induce adverse health effects, and hair, as a biomonitor
for organohalogens assessment, is more recommendable.
Authors:Bálint Alasztics, Nóra Gullai, Attila Molvarec and János Rigó Jr.
placenta cDNA coding for a protein related to the vascular permeability factor. Proc. Natl. Acad. Sci., 1991, 88 (20), 9267–9271.
Majesky, M. W.: A little VEGF goes a long way. Therapeutic angiogenesis by direct
Authors:P. Kovács, József Gábor Joó, V. Tamás, Z. Molnár, D. Burik-Hajas, J. Bódis and L. Kornya
Introduction Programmed cell death (apoptosis) plays an important role during the development of the placenta and in the regulation of its ageing during pregnancy [ 35 ]. The regulation of programmed cell death is complex; both proapoptotic
Human placental tissue from 100 hospitalized deliveries were analysed for Ag, Al, As, Au, B, Ba, Br, Ca, Cd, Cl, Co, Cr, Cs, Cu, F, Fe, I, Hg, K, La, Mg, Mn, Mo, Na, Ni, Rb, S, Sb, Sc, Se, Sn, Sr, Ti, V, W and Zn using a combination of pre-chemical separation of sodium with hydrated antimony pentoxide and instrumental neutron activation analysis. Boron and Si values were determined using prompt gamma-ray and fast-neutron techniques respectively. Analysis of NBS-SRM Bovine Liver 1577 and a pooled standard placental tissue for 33 elements showed a good agreement with most coefficients of variation less than or equal to 15%, and recoveries of 91–104%. Symmetrical distributions, were obtained for all elemental placental values. Only Cd(–) and Zn(+) showed statistically significant correlations with birth weight, gestational age and placental weight. The influence of cigarette smoking is considered a major factor in producing elevated cadmium levels in the placental tissue of smokers and passive smokers, and hence lower birth weights.