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Speer, G.: Pathogenesis and epidemiology of polycystic ovary syndrome. In: Lakatos, P., Speer, G. (eds.). Polycystic ovary syndrome. [A PCOS patogenezise és epidemiológiája. In: Polycystas ovarium szindróma

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Sirmans, S. M., Pate, K. A.: Epidemiology, diagnosis, and management of polycystic ovary syndrome. Clin. Epidemiol., 2014, 6, 1–13. March, W. A., Moore, V. M., Willson, K

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Orvosi Hetilap
Authors:
Orsolya Micskei
,
Tamás Deli
,
Attila Jakab
, and
Antal Bugán

Könyvkiadó, Budapest, 2000. [Hungarian] Dowdy, D.: Emotional needs of teens with polycystic ovary syndrome. J. Pediatr. Nurs., 2012, 27 (1) 55−64. Tabák, R., Kemény, L

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endocrine and metabolic parameters in women with polycystic ovary syndrome. Exp. Clin. Endocrinol. Diabetes, 2010, 118 , 633–637. Jentsch K. D. The effect of metformin treatment for 2

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342 Teede, H., Deeks, A., Moran, L.: Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across

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Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group: Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil. Steril., 2004

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64 501 516 Teede, H., Deeks, A., Moran, L.: Polycystic ovary syndrome: a complex condition with psychological, reproductive and

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, pioglitazone, D-chiro-inositol) for women with polycystic ovary syndrome, oligo-amenorrhoea and subfertility. Cochrane Database Syst. Rev., 2010, Jan 20 (1), CD003053. Lakatos P., Speer G. (szerk

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Acta Physiologica Hungarica
Authors:
Levente Sára
,
GyL. Nádasy
,
P. Antal
,
M. Szekeres
,
A. Monori-Kiss
,
E. Horváth
,
A. Tőkés
,
G. Masszi
,
E. Monos
, and
Szabolcs Várbíró

To clarify the effects of dihydrotestosterone (DHT)-induced polycystic ovary syndrome (PCOS) on arteriolar biomechanics in a rat model and the possible modulatory role of vitamin D3.Methods and Results The PCOS model was induced in female Wistar rats by ten-weeks DHT treatment. Arteriolar biomechanics was tested in arterioles by pressure arteriography in control as well as DHT- and DHT with vitamin D3-treated animals in contracted and passive conditions. Increased wall stress and distensibility as well as increased vascular lumen were detected after DHT treatment. Concomitant vitamin D3 treatment lowered the mechanical load of the arterioles and restored the vascular diameter.Conclusion The hyperandrogenic state resulted in more rigid, less flexible arteriolar walls with increased vascular lumen compared with controls. DHT treatment caused eutrophic remodelling of gracilis arteriole. These prehypertensive alterations caused by chronic DHT treatment were mostly reversed by concomitant vitamin D3 administration.

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1135 Károlyi, Z.: The pathomechanism of polycystic ovary syndrome in the light of novel research findings. [A polycystás ovarium szindróma kialakulásáról az újabb kutatások

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