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Koul, A. K., Hollander, G., Moskovitz, N. és mtsai: Coronary artery dissection during pregnancy and the postpartum period: Two case reports and review of literature. Catheter Cardiovasc. Interv., 2001, 52 , 88
The aim of this study was to determine the effect of increased levels of prolactin (PRL) on the concentration of immunoglobulins in the blood, colostrum and milk of mares. The study was conducted on 12 mares of the Polish Pony breed (6 in the control and 6 in the experimental group). To induce hyperprolactinaemia in mares of the experimental group, 750 mg sulpiride was administered orally once a day. The initial PRL concentration was 52.22 ± 11.21 ng/ml in the control group and 49.39 ± 10.12 ng/ml in the experimental group. In the subsequent days, the concentration of PRL dynamically changed. Statistical analysis showed highly significant differences (P < 0.01) between the groups. The concentration of immunoglobulins in the blood plasma was at the same level during the experimental period (32.97–29.08 mg/ml in the experimental group and 28.60–18.11 mg/ml in the control group). Statistical analysis showed highly significant differences between the groups in blood plasma immunoglobulin level (P < 0.01). The highest immunoglobulin concentration was obtained within 12 h after parturition in the control and the experimental group (23.49 ± 2.12 mg/ml and 26.94 ±1.72 mg/ml, respectively). The lowest values were obtained on day 12 after parturition in the experimental group (10.15 mg/ml ± 1.47 mg/ml) and on day 7 after parturition in the control group (14.30 mg/ml ± 2.48 mg/ml). In conclusion, this study did not provide evidence that the lactogenic hormone prolactin is involved in the transfer of immunoglobulins into the colostrum in horses.
A szerző a terhesség alatt és post partum észlelt pajzsmirigy-megbetegedések kezelésére és diagnózisára vonatkozó lehetőségeket ismerteti, több szakmai társaság által készült és 2012-ben publikált ajánláson keresztül. Bemutatja ezen ajánlás alapjait és meg nem oldott kérdéseit is, különösen a TSH-szűréssel kapcsolatos álláspontokban. Terhességben a hyperthyreosis okai a kezelendő Basedow-kór, az ettől gyakran nehezen megkülönböztethető terhességi, átmeneti thyreotoxicosis, amely nem kezelendő. A post partum thyreoiditis jóval gyakrabban fordul elő pajzsmirigy-peroxidáz-ellenes antitestpozitív nőkben, akik esetén ezért a TSH-szintet a terhesség 6. és 12. hete között, illetve a szülés utáni 3. és 6. hónapban ellenőrizni kell. A hypothyreosis autoimmun eredetű, és nem kizárólag a manifeszt formája, hanem a szubklinikai megjelenése is kezelendő. Minden pajzsmirigybetegség szerepet játszik a meddőség patomechanizmusában is. Orv. Hetil., 2013, 154(51), 2017–2023.
A szerzők közleményükben egy 29 éves, először terhes, először szülő asszony kórtörténetét ismertetik, akinél a terhesség 39. hetében akut intrauterin magzati distress (köldökzsinór-szövődmény) miatt császármetszés, majd az 5. posztoperatív napon gangraneas, perforált appendix eltávolítása történt. A féregnyúlvány hisztológiai vizsgálata a bélfalat teljes vastagságában érintő „agresszív” deciduosist írt le. Közleményükben kitérnek a ritka kórkép tanulságaira. Az esetismertetés az első olyan magyar nyelvű közlemény, amelyben az appendixre lokalizálódó deciduosisról számolnak be, és egyben az első nemzetközi publikáció is, melyben császármetszést követően kialakult deciduosis okozta appendicitis miatt appendectomiára került sor.
The energy imbalance related predisposition to mastitis was studied in group-fed postpartum dairy cows (n = 333) kept in 4 large-scale units and producing milk of low somatic cell count (SCC). Blood samples were taken on Days 1-3 after calving for assaying some metabolites and hormones related to the negative energy balance (NEB). If mastitis was diagnosed later, aseptic milk samples were taken to identify the pathogens. Considering pathogen types [contagious pathogens: Staphylococcus (S.) aureus, Gram-positive (GP) environmental pathogens, and Gram-negative (GN) environmental pathogens + mastitis with no detectable pathogens (NDP)] separately, stepwise logistic regression was used to analyse the relation between the potential prognostic value of hormones and metabolites and mastitis outbreak. Only the elevated (= 1.00 mmol/l) serum ß-hydroxybutyrate (BHB) levels predisposed the cows to mastitis in the subsequent 4 weeks. This prognostic value of BHB was significant only in GN + NDP mastitis and in cases caused by GP environmental pathogens, but not in S. aureus mastitis (odds ratio: 5.333, 3.600 and 1.333, respectively).
Sacher, J., Wilson, A. A., Houle, S. és mtsai: Elevated brain monoamine oxidase. A binding in the early postpartum period. Arch. Gen. Psychiatry, 2010, 67 , 468–474. Houle S. Elevated
-eclamptic patient was mean 52.42 ± 7.0 g (range 36–62 g) over 48 h (this does not exceed the maximum dose of 30–40 g/day). Nifedipine, a calcium-channel blocker, was given orally 3 × 10 mg per 24 h even at the postpartum period. Significantly elevated ( P ≤ 0
All cows but one SPT and one TPS enrolled in the study showed a normal late pregnancy, a normal spontaneous parturition of a single calf followed by placental expulsion, as well as a postpartum period without clinical abnormalities. Therefore, the
Pemphigoid gestationis (PG) is a rare autoimmune blistering disease of pregnancy caused by antibasement membrane zone autoantibodies. The usual clinical findings are multiple pruritic urticarial papules and plaques, target lesions, vesicles, and blisters that occur during the second and third trimesters of pregnancy or in the immediate postpartum period. The disease is often treated with topical corticosteroids and oral antihistaminics. In more severe cases, systemic corticosteroids are needed. Herein, we report a case of resistant PG that responded to treatment with cyclosporine.
This study was designed to compare Coxiella burnetii antibody dynamics in heifers born to vaccinated or non-vaccinated dams in a single high-producing dairy herd chronically infected with the bacterium. Antibody dynamics were examined from birth to the postpartum period in replacement heifers (n = 14) born to non-vaccinated dams (n = 7) or to dams that had been vaccinated on gestation days 171–177 (n = 7) and 192–198. Samples of blood, milk, faeces, vaginal fluid, colostrum and cotyledons (the latter two only at parturition) were obtained in the dams over the period from gestation days 171–177 to postpartum days 91–97. Blood samples were used to detect antibodies against C. burnetii and remaining samples for PCR identification of the bacterium. In their calves/heifers, blood samples for antibody determinations were collected from birth to postpartum at the time points 1–7 and 22–28 days and 3, 6 and 12 months of age; 90–96 and 210–216 days of gestation; and 22–28 days postpartum. All calves were born seronegative for C. burnetii. Irrespective of the shedding status of their mothers (7 were C. burnetii shedders), seroconversion occurred after colostrum intake in all calves born to seropositive cows (n = 9) and in two of three vaccinated seronegative dams. Thereafter antibody titres gradually declined and by 6 months of age all calves were seronegative. Seronegativity persisted until their first postpartum period. These findings indicate that cows vaccinated during advanced pregnancy transfer immunity to their calves via the colostrum. Maternal C. burnetii antibodies in calves persisted for three months in calves born both to seronegative vaccinated and seropositive dams.
