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Introduction Psilocybin (4-phosphoryloxy-N,N-dimethyltryptamine) is the main psychoactive, naturally occurring alkaloid in over 200 species of mushrooms worldwide. As the prodrug of psilocin (4-OH-dimethyltryptamine), these compounds act in

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Introduction What is psilocybin? Psilocybin is a psychoactive compound that can induce psychedelic effects ( Griffiths, Richards, McCann, & Jesse, 2006 ). It is a tryptamine alkaloid that naturally occurs in a variety of Psilocybe mushroom species

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Journal of Psychedelic Studies
Authors:
Henrik Børsting Jacobsen
,
Audun Stubhaug
,
Bjørn Holmøy
,
Tor Morten Kvam
, and
Silje Endresen Reme

Introduction Psilocybin, or 4-phosphoryloxy-N,N-dimethyltryptamine, is a hallucinogenic compound that is one of a few active constituents contained in a variety of mushrooms, most in the family psilocybe, referred to as “magic mushrooms”. In recent

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Journal of Psychedelic Studies
Authors:
Kelley C. O’Donnell
,
Sarah E. Mennenga
, and
Michael P. Bogenschutz

Introduction Although clinical research on classic psychedelics [e.g., psilocybin, lysergic acid diethylamide (LSD), and ayahuasca] dates back almost 70 years, its current iteration is relatively new. The number of groups

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Mental health, drug use, and personality as explainers of attitudes towards psilocybin-assisted therapy The prevalence of mental illness is growing worldwide ( World Health Organisation, 2022 ). An emerging mental health treatment involves use of

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The effect of group-administered psilocybin on psychological flexibility and outcomes Research on the efficacy of psychedelic-assisted therapy (PAT) has expanded rapidly in the last decade. The FDA has designated breakthrough therapy status for MDMA

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Introduction The last decade has witnessed a resurgence of interest in serotonergic psychedelics, such as lysergic acid diethylamide (LSD) and psilocybin, for the treatment of a range of psychopathologies. Whilst individuals self-medicate with

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Journal of Psychedelic Studies
Authors:
Sam Elias
,
Stephanie Spivak
,
Alexa Alverez
,
Alejandro Gili Olivares
,
Maria Ferrol
, and
Julian Paul Keenan

Introduction It is of scientific interest to discover the influence psilocybin has on an individual's self-awareness. As psilocybin becomes more common as a treatment for mental disorders it is critical that we understand how one's self

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Introduction Psilocybin is currently being used in numerous clinical studies for its benefits in the treatment of psychiatric disorders including depression ( Davis et al., 2021 ), anxiety ( Agin-Liebes et al., 2020 ), and substance use disorders

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Journal of Psychedelic Studies
Authors:
John M. Clifton
,
Annabelle M. Belcher
,
Aaron D. Greenblatt
,
Christopher M. Welsh
,
Thomas O. Cole
, and
Alan K. Davis

; Guerrero et al., 2017 ; Hewell, Vasquez, & Rivkin, 2017 ; Lagisetty, Ross, Bohnert, Clay, & Maust, 2019 ; Sharma et al., 2017 ; Truong et al., 2019 ). Psilocybin is a “classic psychedelic” that exerts its psychological effects through 5-HT2A

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