Search Results

You are looking at 1 - 10 of 71 items for :

  • "psoriasis" x
Clear All
Orvosi Hetilap
Authors: Iván Péter, Anna Jagicza, Zénó Ajtay, István Kiss and Balázs Németh

References 1 Parisi, R., Symmons, D. P., Griffiths, C. E., et al.: Global epidemiology of psoriasis: a systematic review of incidence and prevalence. J

Restricted access
Acta Microbiologica et Immunologica Hungarica
Authors: Elaheh Vanaki, Mitra Ataei, Mohammad Sanati, Parvine Mansouri, Mahmoud Mahmoudi, Feresteh Zarei and Zohreh Jadali

Monteleone, G., Pallone, F., MacDonald, T.T., Chimenti, S., Costanzo, A.: Psoriasis: From pathogenesis to novel therapeutic approaches. Clin Sci (Lond) 120 , 1–11 (2011

Restricted access
Orvosi Hetilap
Authors: Fanni Rencz, Valentin Brodszky, Márta Péntek, Orsolya Balogh, Éva Remenyik, Andrea Szegedi, Péter Holló, Sarolta Kárpáti, Hajnalka Jókai, Krisztina Herszényi, Emese Herédi, Sándor Szántó and László Gulácsi

Nestle, F. O., Kaplan, D. H., Barker, J.: Psoriasis. N. Engl. J. Med., 2009, 361 (5), 496–509. Weger, W.: An update on the diagnosis and management of psoriatic arthritis

Open access
Orvosi Hetilap
Authors: L. János Kálmán, Xénia Gonda, Lajos Kemény, Zoltán Rihmer and Zoltán Janka

Gyulai, R., Kemény, L.: The immunology of psoriasis: from basic research to the bedside. [A psoriasis immunológiája: alapkutatástól a betegágyig.] Orv. Hetil., 2006, 147 (46), 2213–2220. [Hungarian

Open access

acids in HPLC. According to this result, the new HPLC method conditions with a simple sample pretreatment were developed. Psoriasis is a serious, heterogeneous, systemic immune disease with obvious genetic predisposition and autoimmune characteristics

Open access
Orvosi Hetilap
Authors: Adrienn Katalin Poór, Miklós Sárdy, Tamás Cserni, Valentin Brodszky, Péter Holló, László Gulácsi, Éva Remenyik, Andrea Szegedi, Fanni Rencz and Márta Péntek

References 1 Michalek IM, Loring B, John SM. A systematic review of worldwide epidemiology of psoriasis. J Eur Acad Dermatol Venereol. 2017; 31: 205

Open access
Orvosi Hetilap
Authors: Nóra Gyöngyösi, Kende Lőrincz, Sarolta Kárpáti and Norbert Wikonkál

, B. S.: Triggering psoriasis: the role of infections and medications. Clin. Dermatol., 2007, 25 , 606–615. Baker B. S. Triggering psoriasis: the role of infections and medications

Open access

in patients with psoriasis (CHAMPION). Br. J. Dermatol., 2008, 158 , 558–566. Dubertret L. Efficacy and safety results from the randomized controlled comparative study of

Open access

Calcium plays an important role in the regulation of different functions of keratinocytes. In the present work we studied the effect of different extracellular calcium concentrations (0.01 mM-2.0 mM) on the proliferation and differentiation of human keratinocytes in normal human and non-lesional psoriatic skin. Using explant culture model, the proliferative and differentiated subsets of keratinocytes were detected by specific antibodies related to cell proliferation [beta-1 integrin (CD29), proliferating cell antigen (Ki67), proliferating cell nuclear antigen (PCNA)] and differentiation [differentiated cell cytokeratins (K1/K10) and differentiating cell antigen (lectin Ulex europaius agglutinin, UEA-1)]. After 4 days of culturing at high Ca2+ (2.0 mM) we observed marked hyperproliferation among the normally quiescent keratinocytes of non-lesional psoriatic skin. In normal uncultured and cultured skin and in uncultured and two-day-cultured non-lesional psoriatic skin both at normal (1.2 mM) and at high (2.0 mM) Ca2+ concentration only one layer of basal CD29+/Ki67+/K1/K10-/UEA-1- cell was observed. In sections from non-lesional psoriatic skin cultured for 4 days in the presence of high Ca2+ (2.0 mM) this cell population has expanded from at least three layers above the basement membrane. This expanded cell population of the 4-day high Ca2+ cultured non-lesional skin showed clear PCNA positive staining on frozen sections with the strongest positivity among the most basal localized cells. These data suggest that (i) extracellular Ca2+ concentration can influence the proliferation of basal ("stem") keratinocytes, (ii) the proliferative response to high Ca2+ concentration of psoriatic non-lesional basal keratinocytes differs from that of normal basal keratinocytes, (iv) changes in the extracellular Ca2+ milieu might play a role in the induction of the hyperproliferative psoriatic lesion.

Restricted access
Orvosi Hetilap
Authors: Gabriella Nagy, Katalin Lukács, Ágnes Sziray, Katalin Fazekas, Ágnes Florián, László Tamási and Zsuzsánna Károlyi

Boehncke, W-H.: Biologics in the treatment of psoriasis. In: Evidence-based therapy of psoriasis: Focus on biologics. Eds: Boehncke, W-H., Kaufman, R. Uni-Med Verlag AG, Bremen, 2008, 88

Restricted access