The serotonin transporter, SERT, is reported as a key molecule that regulates serotonergic neurotransmission. In the present study, we analyzed the localization of
SERT (LymSERT) mRNA-containing neurons by
hybridization using frozen sections of the central nervous system (CNS) of
. To precisely demonstrate the distribution of LymSERT mRNA-containing neurons, colocalization with serotonin immunoreactivity was also examined. The results showed that LymSERT mRNA was constitutively expressed and localized in the serotonin-containing neurons in the CNS.
. , Belmaker , R. H. , Ebstein , R. P. ( 2003 ): Relation of shyness in grade school children to the genotype for the long form of the serotonintransporter promoter region polymorphism . American Journal of Psychiatry , 160 , 671 – 676
Authors:Julia O Fedotova, G Hartmann, L Lénárd and NS Sapronov
Manswood S, Truitt W, Hotema M, Caldarola-Pastuszka M: Estrous cycle modulation of extracellular serotonin in mediobasal hypothalamus: role of the serotonintransporter and terminal autoreceptors. Brain Res. 831, 146