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. 78. J.T. Bruder I. Kovesdi 1997 Adenovirus infection stimulates the Raf/MAPK signaling pathway and induces interleukin-8

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) Endothelin 1 and 3 enhance neuronal nitric oxide synthase activity through ETB receptors involving multiple signalling pathways in rat anterior hypothalamus. Peptides 25 , 1133–1138. Vatta M. S

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Interventional Medicine and Applied Science
Authors: Igor Rabelo de França, Daniela Meneses-Santos, Gabriela Virginia Moreira, Fábio Bessa Lima, Carla Roberta de Oliveira Carvalho, and Anderson Carlos Marçal

molecular adjustments in the level and/or degree of phosphorylation of proteins involved in the intracellular insulin receptor/insulin-like growth factor receptor (IR/IGF1R) signaling pathway [ 10 – 15 ]. Proteins located downstream of the IR/IGF1

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. , Trautwein , C. : Signaling pathways in liver diseases , 2nd Edition DOI: 10.1007/978-3-642-00150-5, Springer, 2010 , pp. 68. Re , F. , Strominger , J. L. : Toll-like receptor

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with luteolin ameliorates retinal apoptosis in diabetic retinopathy rats by regulating the NLRP1/NLRP3/ NOX4 signalling pathway. Thus, luteolin could be used clinically for the management of diabetic retinopathy. Ethics approval and consent to

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). Among dozens of molecular mediators related to angiogenesis, protein kinase B (AKT) and extracellular signal-regulated kinase (ERK 1/2) signaling pathways are significant as they control proliferation and survival of endothelial cells. There are

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12 239 246 Ceppi M, Pereira PM, Dunand-Sauthier I, Barras E, Reith W, Santos MA, Pierre P: MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells. Proc

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pathway leads to hypertrophy [ 2 ]; one of the main factors in this signaling pathway is IGF-I, which stimulates muscle fiber growth by activating an intracellular cascade [ 3 ]. In addition, the IGF-I/Akt pathway can inhibit translocation of the forkhead

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–1876. Haluska, F. G., Tsao, H., Wu, H., et al.: Genetic alterations in signaling pathways in melanoma. Clin. Cancer Res., 2006, 12 (7 Pt 2), 2301s–2307s. Lang, J., Boxer, M., MacKie, R.: Absence of exon 15 BRAF germline

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reported as a general metabolic regulator ( 29 ). In addition, Wnt plays a critical role in modulations of cell growth, apoptosis, and in the process of gene expression of cell self-renewal ( 72 ). There are many signal pathways involved in an

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