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had developed ESKD after a follow-up of 74 months. Conversely, in the group with creatinine clearance <70 ml/min, the rate of creatinine clearance decline was not modified by steroid treatment. Among adverse effects, avascular necrosis of the femoral

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Ireland, J. J. and Roche, J. F. (1983): Development of nonovulatory antral follicles in heifers, changes in steroids in follicular fluid and receptors for gonadotropins. Endocrinology 112 , 150-156. Development of nonovulatory

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Summary

A simple, rapid, and sensitive high-performance liquid chromatography method was developed and validated for the simultaneous determination and quantification of fusidic acid and steroids (prednisone, betamethasone valerate, hydrocortisone acetate, and dexamethasone sodium) from bulk drugs and human plasma. A RP-HPLC, operated at ambient temperature, was equipped with a UV detector for monitoring the effluents at 235 nm. The mobile phase consisted of methanol, acetonitrile, and 0.05 M phosphoric acid (10:60:30, v/v/v), and separation was achieved on a Medeterrane, C18 (5 μm, 12.5 × 0.46 mm) column at a flow rate of 1.7 mL min−1. Calibration curves were linear over concentration range 0.625–10 μg mL−1 with correlation coefficient (r 2) greater than 0.9999. The coefficient of variation (CV) and relative error (RE) for intra- and interassay were <2% and <1%, respectively. Interference of other already administered common medicaments, such as aspirin, paracetamol, caffeine, nicotine, and other plasma components, were not found.

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Acta Veterinaria Hungarica
Authors: Marek Opalka, Justyna Kugla-Owczarska, Barbara Kaminska, Helena Puchajda-Skowronska, Wioletta Hryniewicka and Luiza Dusza

Szafranska, B., Ziecik, A. and Okrasa, S. (2002): Primary antisera against selected steroids or proteins and secondary antisera against γ-globulins — an available tool for studies of reproductive processes. Reprod. Biol. 2 , 187

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Tóth, M., Hertelendy, F.: Androgen binding and androgen effect in the rat seminal vesicles: studies with testosterone and 19-nortestosterone. J. Steroid Biochem. Mol. Biol., 1979, 11 , 1091

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Balthazart, J. (1997) Steroid control and sexual differentiation of brain aromatase. J. Steroid Biochem. Molec. Biol. 61 , 323–339. Balthazart J. Steroid control and sexual

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Baulieu, E. E., Robel, P.: Neurosteroids: a new brain function? J. Steroid Biochem. Mol. Biol., 1990, 37 , 395–403. (abstr.) Robel P. Neurosteroids: a new brain function

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Andersson, S., Russell, D. W. (1990) Structural and biochemical properties of cloned and expressed human and rat steroid 5α-reductases. Proc. Natl. Acad. Sci. USA 87 , 3640

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B. Tinant G. Pocsfalvi B.A. Šolaja 2005 Steroids 70

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JPC - Journal of Planar Chromatography - Modern TLC
Authors: Bogdan Tiťa, Olivia Măruťoiu, Dumitru Tiťa, Constantin Măruťoiu, Maria Soran and Zaharia Moldovan

M. Pitea, D. Ghiran, A. Mureoan , Medicamente antiinflamatoare nesteroidiene (Non-steroidal anti-inflammatory drugs), Ed. Dacia, Cluj-Napoca, 1997. Mureoan A

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